Pre ‐pregnancy weight excess and body mass index: Analysis of three generations Brazilian birth cohort

SummaryTo evaluate the relationship between the grandmother's maternal pre-pregnancy body mass index (BMI) (first generation —G1), the BMI of the female members of the birth cohort of Pelotas/RS, Brazil, 1993 (second generation—G2) and the children of the cohort members (third generation—G3). a longitudinal study using data from the 1993 Pelotas/RS cohort. The maternal pre-pregnancy BMI of the mothers of the members (first generation—G1) was self-reported, and of the participants in the cohort (second generation—G2) was collected using weight and height in follow-ups prior to 22 years of age. Children from the third generation (G3) were included in this last follow-up (22 years) and anthropometric meas urements were collected. The outcome was BMI-for-agez-score obtained using weight and height measures collected in every follow-up. Linear regression was performed with adjustment for possible confounding factors. The cohort's original sample consists of 5249 participants and 855 children (their first children). At 12 and 48  months, the average increase in BMI-for-agez-score of children of women with pre-pregnancy weight excess was 0.11 and 0.47 kg/m2, respectively, increasing to around 0.60 kg/m2 in adolescence, reaching an average increase of 2.71 kg/m2 in BMI at 22  years of age. The G2 pre-pregnancy weight excess was also associated with G3 BMI-for-agez-score [β = 0.43 kg/m2 (95% CI 0.21; 0.65)]. Maternal pre-pregnancy weight excess was associated with...
Source: Clinical Obesity - Category: Eating Disorders & Weight Management Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research