Connectome-based biophysics models of Alzheimer ’s disease diagnosis and prognosis

With the increasing prevalence of Alzheimer ’s disease (AD) among aging populations and the limited therapeutic options available to slow or reverse its progression, the need has never been greater for improved diagnostic tools for identifying patients in the preclinical and prodomal phases of AD. Biophysics models of the connectome-based s pread of amyloid-beta (Aβ) and microtubule-associated protein tau (τ) have enjoyed recent success as tools for predicting the time course of AD-related pathological changes.

Source: Translational Research - August 28, 2022 Category: Research Authors: Justin Torok, Chaitali Anand, Parul Verma, Ashish Raj Source Type: research