Acute Kidney Injury Associates with Long-Term Increases in Plasma TNFR1, TNFR2, and KIM-1: Findings from the CRIC Study

Conclusions
Among patients with CKD, AKI during hospitalization was associated with increases in plasma TNFR1, TNFR2, and KIM-1 several months after their hospitalization. These results highlight a potential mechanism by which AKI may contribute to more rapid loss of kidney function months to years after the acute insult.

Source: Journal of the American Society of Nephrology : JASN - May 31, 2022 Category: Urology & Nephrology Authors: McCoy, I. E., Hsu, J. Y., Bonventre, J. V., Parikh, C. R., Go, A. S., Liu, K. D., Ricardo, A. C., Srivastava, A., Cohen, D. L., He, J., Chen, J., Rao, P. S., Hsu, C.-y., on behalf of the Chronic Renal Insufficiency Cohort (CRIC) Study Investigators, Chron Tags: Acute Kidney Injury Source Type: research