Ectodysplasin-A mRNA in exosomes released from activated hepatic stellate cells stimulates macrophage response

CONCLUSIONS: HSC activation leads to altered EXO mRNA/miRNA profiles with aHSC-EXOs mRNAs exerting a dominant role in altering macrophage function. Ectodysplasin-A mRNA is an important component in aHSC-EXOs in regulating macrophage function.PMID:35964664 | DOI:10.1016/j.yexcr.2022.113297

Source: Experimental Cell Research - August 14, 2022 Category: Cytology Authors: Emilio Marrero Neha Attal Ali Nimeri Rachel M McGee Jennifer H Benbow Kyle J Thompson Laura W Schrum Iain H McKillop Source Type: research