The mismatch-repair proteins MSH2 and MSH6 interact with the imprinting control regions through the ZFP57-KAP1 complex

Imprinting Control Regions (ICRs) are CpG-rich sequences acquiring differential methylation in the female and male germline and maintaining it in a parental origin-specific manner in somatic cells. Despite the...

Source: Epigenetics and Chromatin - August 2, 2022 Category: Genetics & Stem Cells Authors: Basilia Acurzio, Francesco Cecere, Carlo Giaccari, Ankit Verma, Rosita Russo, Mariangela Valletta, Bruno Hay Mele, Claudia Angelini, Angela Chambery and Andrea Riccio Tags: Research Source Type: research