Cellular senescence: the good, the bad and the unknown

Nature Reviews Nephrology, Published online: 03 August 2022; doi:10.1038/s41581-022-00601-zCellular senescence has beneficial functions in embryonic development, wound healing and tumour suppression but can also be maladaptive, contributing to cancer development and disease. This Review describes the mechanisms, hallmarks and consequences of senescence, as well as the therapeutic potential of senescence-targeting interventions.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Source Type: research