The Pathological and Clinical Diversity of Acute Vascular Rejection in Kidney Transplantation

Background. Vascular rejection (VR) is characterized by arteritis, steroid resistance, and increased graft loss but is poorly described using modern diagnostics. Methods. We screened 3715 consecutive biopsies and retrospectively evaluated clinical and histological phenotypes of VR (n = 100) against rejection without arteritis (v0REJ, n = 540) and normal controls (n = 1108). Results. Biopsy sample size affected the likelihood of arterial sampling, VR diagnosis, and final Banff v scores (P
Source: Transplantation - Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research