Identification of a novel FGFR2-KIAA1217 fusion in oesophageal gastrointestinal stromal tumours: A case report

Conclusion: To the best of our knowledge, this report is the first to describe an FGFR2-KIAA1217 fusion in a patient with a quadruple WT oesophageal GIST. When WT KIT/PDGFRA GISTS are suspected, intensive genetic analysis is recommended, and obtaining a better molecular characterization of these tumours might reveal novel therapeutic avenues.

https://www.frontiersin.org/articles/10.3389/fonc.2022.884814

Source: Frontiers in Oncology - August 1, 2022 Category: Cancer & Oncology Source Type: research