Renal denervation reduces atrial remodeling in hypertensive rats with metabolic syndrome

In conclusion, suppression of renal sympathetic nerve activity by RDN prevents atrial remodeling in metabolic syndrome by reducing atrial sympathetic innervation and by modulating RAGE/sRAGE balance and reducing pro-inflammatory and pro-fibrotic RAGE ligands, which provides a potential therapeutic mechanism to reduce the development of AF.
Source: Basic Research in Cardiology - Category: Cardiology Source Type: research