α-Gal antigen-deficient rabbits with GGTA1 gene disruption via CRISPR/Cas9

Previous studies have identified the carbohydrate epitope Gal α1–3Galβ1–4GlcNAc-R (termed the α-galactosyl epitope), known as the α-Gal antigen as the primary xenoantigen recognized by the human immune system. ...

Source: BMC Genetics - July 11, 2022 Category: Genetics & Stem Cells Authors: Lina Wei, Yufeng Mu, Jichao Deng, Yong Wu, Ying Qiao, Kun Zhang, Xuewen Wang, Wenpeng Huang, Anliang Shao, Liang Chen, Yang Zhang, Zhanjun Li, Liangxue Lai, Shuxin Qu and Liming Xu Tags: Research Source Type: research