Ceramides and sphingolipids are more than simple building blocks

AbstractCeramides and sphingolipids are long chain fatty acids, which are components of the stratum corneum layer of the skin. The composition of ceramides, sphingolipids and other lipids is important for the formation of a healthy skin barrier, which may be compromised in skin conditions such as atopic dermatitis and psoriasis. Ceramides and sphingolipids are also involved in the control of keratinocyte proliferation and differentiation, as well as modulating the immune system within the skin. Nutraceutical products with ceramides or sphingolipids are currently available and recent studies identified potential benefits of topical ceramide products in patients with atopic dermatitis or psoriasis.
Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research