Stroke in ATTR cardiac amyloidosis: Does only rhythm matter?

Transthyretin amyloidosis (ATTR) is frequently associated with cardiac involvement in the wild type form (wtATTR) as well as in the mutated form (variant ATTR, vATTR). Although left ventricular (LV) pseudohypertrophy is currently considered the most relevant structural abnormality in cardiac amyloidosis (CA), atrial involvement due to both amyloid infiltration and secondary to LV overload and remodeling, is another key feature and a major determinant of decompensation, especially when associated with atrial arrhythmias [1].
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research