Therapeutic cancer vaccines: From biological mechanisms and engineering to ongoing clinical trials

Cancer is a significant health problem, with nearly 10 million deaths every year [1]. Besides protecting the organism from pathogens, the immune system's role is also useful for surveying the body to maintain cellular homeostasis. However, tumor cells can escape immune surveillance either by a selection of non-immunogenic tumor cell variants (immunoselection) or by actively suppressing immune response (immunesubversion)[2]. Advancements in immunotherapy have brought forth new potential therapies and prophylactic treatments that could lead to anticancer vaccines.
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Anti-tumour Treatment Source Type: research