The clinical treatment of bacterial keratitis: A review of drop instillation regimes

Bacterial keratitis (BK) presentations are often treated using the commercially available second-generation fluoroquinolones ciprofloxacin 0.3% and ofloxacin 0.3% as monotherapy. The guidelines available for instillation regimes are often not supported by data from clinical studies.This review examines the peer-reviewed clinical studies and compared treatment failure rates for ciprofloxacin 0.3% and ofloxacin 0.3% for BK in relation to Day-1 drop-regimes. From the statistical analysis, this review derived evidence-based clinically applicable minimum drop-regimes for the treatment of BK on Day-1.

Source: Contact Lens and Anterior Eye - June 17, 2022 Category: Opthalmology Authors: John G Pearce, Rohan W Essex, Ted Maddess Tags: Review article Source Type: research