MRI reveals functional brain alterations associated with depression
Researchers have found that MRI reveals functional brain alterations that are associated with major depression, according to a study published February 19 in JAMA Network Open.
The study results could help clinicians better care for depressed patients, wrote a team led by Xinyi Wang of Southeast University, Nanjing, China.
"[Major] depressive disorder (MDD) is associated with reduced quality of life and increased risk of suicide and self-wounding," Wang and colleagues noted. "Understanding the neurobiological mechanisms underlying depression is a crucial aspect of developing improved therapeutic options and minimizing ad...
Source: AuntMinnie.com Headlines - February 19, 2024 Category: Radiology Authors: Kate Madden Yee Tags: Subspecialties Neuroradiology Source Type: news
The impact of complex PTSD on suicide risk in patients with bipolar disorder: a cross-sectional study - Iazzolino AM, Valenza M, D'Angelo M, Longobardi G, Stefano VD, Visalli G, Steardo L, Scuderi C, Steardo L.
BACKGROUND: Patients with bipolar disorder (BD) are more likely than the general population to experience traumatic events, particularly during childhood, and these may predict and be a risk factor for the development of complex PTSD (cPTSD). The presence ... (Source: SafetyLit)
Source: SafetyLit - February 9, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
How to Diagnose and Treat Bipolar Disorder How to Diagnose and Treat Bipolar Disorder
The Curbsiders share their favorite pearls about managing bipolar disorder in the primary care setting.The Curbsiders (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 5, 2024 Category: Consumer Health News Tags: Internal Medicine Commentary Source Type: news
Blood epigenome-wide association studies of suicide attempt in adults with bipolar disorder - Mirza S, Lima CNC, Del Favero-Campbell A, Rubinstein A, Topolski N, Cabrera-Mendoza B, Kov ács EHC, Blumberg HP, Richards JG, Williams AJ, Wemmie JA, Magnotta VA, Fiedorowicz JG, Gaine ME, Walss-Bass C, Quevedo J, Soares JC, Fries GR.
Suicide attempt (SA) risk is elevated in individuals with bipolar disorder (BD), and DNA methylation patterns may serve as possible biomarkers of SA. We conducted epigenome-wide association studies (EWAS) of blood DNA methylation associated with BD and SA.... (Source: SafetyLit)
Source: SafetyLit - February 2, 2024 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Gray matter biomarkers for major depressive disorder and manic disorder using logistic regression - Kumar M, Goyal P, Sagar R, Kumaran SS.
The study investigates morphometric changes using surface-based measures and logistic regression in Major depressive-disorder (MDD) and Manic-disorder patients as compared to controls. MDD (n = 21) and manic (n = 20) subjects were recruited from psychiatri... (Source: SafetyLit)
Source: SafetyLit - February 2, 2024 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Schizophrenia Med Safe, Effective for Bipolar Mania Schizophrenia Med Safe, Effective for Bipolar Mania
Iloperidone, an atypical antipsychotic approved for schizophrenia, appears to be safe and effective in the treatment of bipolar mania, phase 3 results of an RCT showed.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - February 1, 2024 Category: Drugs & Pharmacology Tags: Psychiatry Source Type: news
Bipolar disorder due to traumatic brain injury: a case report - Altuwairqi Y.
I report an unusual case in Saudi Arabia of a 28-year-old man who had bipolar disorder due to a traumatic brain injury suffered 10 years previously. He had been evaluated and diagnosed with schizoaffective disorder as well as amphetamine and hash use disor... (Source: SafetyLit)
Source: SafetyLit - February 1, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Bipolar disorder and cumulative trauma: a systematic review of prevalence and illness outcomes - Rowe AL, Perich T, Meade T.
BACKGROUND: The experience of cumulative trauma may be common in bipolar disorder (BD). However, it is not frequently reported as most studies focus on childhood trauma without examining differences in the amount of trauma experienced. This systematic revi... (Source: SafetyLit)
Source: SafetyLit - January 30, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Lithium treatment may promote bone health in women with bipolar disorder
Women taking lithium for bipolar disorder had greater bone mineral density on dual-energy x-ray absorptiometry (DEXA) exams compared to women with bipolar disorder not taking the medication, according to a recent study.The finding reinforces the role of lithium as a first-line therapy, with recent research suggesting that patients with bipolar disorder are disproportionately affected by osteoporosis and have an increased risk of fracture, noted first author Lana Williams, PhD, of Deakin University in Victoria, Australia, and colleagues.“Both the condition and the medications used to treat it, for example, antipsychotics ...
Source: AuntMinnie.com Headlines - January 26, 2024 Category: Radiology Authors: Will Morton Tags: Subspecialties Digital X-Ray Musculoskeletal Radiology Source Type: news
What came first, mania or depression? Polarity at onset in bipolar I and II: temperament and clinical course - Janiri D, Simonetti A, Moccia L, Hirsch D, Montanari S, Mazza M, Di Nicola M, Kotzalidis GD, Sani G.
(1) Background: Bipolar disorder (BD) is divided into type I (BD-I) and type II (BD-II). Polarity at onset (PO) is a proposal to specify the clinical course of BD, based on the type of the first episode at disorder onset-depressive (D-PO) or manic (M-PO). ... (Source: SafetyLit)
Source: SafetyLit - January 24, 2024 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
A comparative study of cognitive function in young patients with bipolar disorder with and without non-suicidal self-injury - Hu Z, Han Y, Hu M, Zhang H, Yuan X, Yu H.
OBJECTIVE: Bipolar disorder (BD) is a chronic mental disorder characterized by alternating or mixed episodes of mania or hypomania and depression. Cognitive function impairment is a frequent associated feature of the disease. While many BD patients also en... (Source: SafetyLit)
Source: SafetyLit - January 18, 2024 Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news
Can ictal SPECT make a comeback in epilepsy patients?
A feasibility study could could revive interest in SPECT seizure imaging to help neurosurgeons guide brain surgery in epilepsy patients, according to a team in Switzerland.The researchers leveraged what they described as an untapped opportunity that allowed them to perform SPECT just seconds after triggering seizures, with the imaging visualizing brain regions associated with language difficulties in three patients, noted lead author Sabry Barlatey, MD, PhD, of University Hospital of Bern, and colleagues.“We show that triggering of seizures with direct electric stimulation for ictal SPECT imaging is convenient, spares re...
Source: AuntMinnie.com Headlines - January 16, 2024 Category: Radiology Authors: Will Morton Tags: Subspecialties Neuroradiology Source Type: news
Exploring the relationship between attributional style measured in virtual reality and bullying among children at familial high risk of schizophrenia or bipolar disorder compared with controls - S øndergaard A, Gregersen M, Wilms M, Brandt JM, Hjorthøj C, Ohland J, Rohd SB, Hemager N, Andreassen AK, Knudsen CB, Veddum L, Krantz MF, Greve A, Bliksted V, Mors O, Valmaggia L, Thorup AE, Nordentoft M.
BACKGROUND: Children of parents with severe mental illness report bullying more often compared with controls. We hypothesized that deviations in attributional styles may explain the increased prevalence of bullying experiences. We aimed to assess real-time... (Source: SafetyLit)
Source: SafetyLit - January 16, 2024 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Supporting people with serious mental illness after prison release: the FIT Wellness Model - Zarzar TR, Rosen DL, Ashkin EA.
People with serious mental illness (such as schizophrenia, schizoaffective disorder, or bipolar I disorder) constitute a disproportionate share of the United States prison population. Like people in the general prison population, nearly all individuals wit... (Source: SafetyLit)
Source: SafetyLit - January 15, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Mortality and lithium-protective effects after first-episode mania diagnosis in bipolar disorder: a nationwide retrospective cohort study in Taiwan - Carvalho AF, Hsu CW, Vieta E, Solmi M, Marx W, Berk M, Liang CS, Tseng PT, Wang LJ.
This study aimed to estimate all-cause mortality in patients after a first-episode mania (FEM) and examine whether six guideline-recommended medications can reduce mortality. METHODS: The cohort included population-based FEM samples a... (Source: SafetyLit)
Source: SafetyLit - January 15, 2024 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
