Specialized Centers of Research Excellence (SCORE) on Sex Differences (U54 Clinical Trial Optional)
Funding Opportunity RFA-OD-19-013 from the NIH Guide for Grants and Contracts. The ORWH and participating organizations and institutes seek applications for Specialized Centers of Research Excellence (SCORE) on Sex Differences. The Centers of Excellence will support interdisciplinary approaches to advance translational research on sex differences. Each SCORE institution should develop a research agenda bridging basic and clinical research underlying a health issue that is pertinent to improving the health of women. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 26, 2018 Category: Research Source Type: funding

Specialized Centers of Research Excellence (SCORE) on Sex Differences (U54 Clinical Trial Optional)
The ORWH and participating organizations and institutes seek applications for Specialized Centers of Research Excellence (SCORE) on Sex Differences. The Centers of Excellence will support interdisciplinary approaches to advance translational research on sex differences. Each SCORE institution should develop a research agenda bridging basic and clinical research underlying a health issue that is pertinent to improving the health of women.Tamara Bavendam, MD, MS;Frank Hamilton, MD, MPH;Barbara Linder, MD, PhD | RFA-OD-19-013 (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - November 26, 2018 Category: Endocrinology Source Type: funding

Understanding Age in the NIH Portfolio: Implementation of the NIH Inclusion Across the Lifespan Policy
Dawn Corbett, M.P.H., NIH’s Inclusion Policy Officer Last December, NIH announced a revision to its Inclusion of Children Policy to expand the policy to individuals of all ages (NOT-OD-18-116). The revised policy, now called the Inclusion Across the Lifespan policy, requires individuals of all ages (including children and older adults) be included in clinical research studies unless there are scientific or ethical reasons to exclude them (see also this Open Mike post and this All About Grants podcast). A recent Viewpoint Essay published in the Journal of the American Medical Association (JAMA), co-authored by Drs. M...
Source: NIH Extramural Nexus - November 13, 2018 Category: Research Authors: Dawn Corbett and Michael Lauer Tags: blog Open Mike Inclusion RFI Source Type: funding

Request for Information (RFI): Understanding the Health of Women and the Role of Sex/Gender in Mechanisms of Heart, Lung, Blood, and Sleep Diseases and Disorders
Notice NOT-HL-18-660 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 23, 2018 Category: Research Source Type: funding

Understanding the Glycemic Profile of Pregnancy - Clinical Centers (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-DK-18-018 from the NIH Guide for Grants and Contracts. This FOA invites applications for Clinical Centers to carefully characterize the normal course of glycemia over the entire duration of pregnancy and understand the evolution of dysglycemia when it occurs. Clinical Centers will recruit and study pregnant women starting in the first trimester and continuing at least through delivery. A separate FOA (RFA-DK-18-019) will solicit a Biostatistics Research Center. Each Clinical Center applicant will propose a study design and provide detailed information about recruitment capacity. All awardees will...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 11, 2018 Category: Research Source Type: funding

Understanding the Glycemic Profile of Pregnancy - Biostatistics Research Center (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-DK-18-019 from the NIH Guide for Grants and Contracts. This FOA invites applications for a Biostatistics Research Center to participate in a clinical consortium to carefully characterize the course of glycemia over the entire duration of pregnancy and understand the evolution of dysglycemia when it occurs. A separate FOA (RFA-DK-18-018) invites Clinical Centers to recruit and study pregnant women starting in the first trimester, and continuing at least through delivery. All awardees will form a cooperative research consortium in conjunction with NIDDK to design and implement a uniform protocol. I...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 11, 2018 Category: Research Source Type: funding

Understanding the Glycemic Profile of Pregnancy - Clinical Centers (U01 Clinical Trial Not Allowed)
This FOA invites applications for Clinical Centers to carefully characterize the normal course of glycemia over the entire duration of pregnancy and understand the evolution of dysglycemia when it occurs. Clinical Centers will recruit and study pregnant women starting in the first trimester and continuing at least through delivery. A separate FOA (RFA-DK-18-019) will solicit a Biostatistics Research Center. Each Clinical Center applicant will propose a study design and provide detailed information about recruitment capacity. All awardees will form a cooperative research consortium in conjunction with NIDDK to design and im...
Source: NIDDK Funding Opportunities - October 11, 2018 Category: Endocrinology Source Type: funding

Understanding the Glycemic Profile of Pregnancy - Biostatistics Research Center (U01 Clinical Trial Not Allowed)
This FOA invites applications for a Biostatistics Research Center to participate in a clinical consortium to carefully characterize the course of glycemia over the entire duration of pregnancy and understand the evolution of dysglycemia when it occurs. A separate FOA (RFA-DK-18-018) invites Clinical Centers to recruit and study pregnant women starting in the first trimester, and continuing at least through delivery. All awardees will form a cooperative research consortium in conjunction with NIDDK to design and implement a uniform protocol. Information obtained from this study is expected to lead to improved approaches for...
Source: NIDDK Funding Opportunities - October 11, 2018 Category: Endocrinology Source Type: funding

Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-18-043 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and validation of novel therapeutic targets to facilitate the development of pain therapeutics. Specifically, the focus of this FOA is on the basic science discovery of targets in the peripheral nervous system, central nervous system, immune system or other tissues in the body that can be used to develop treatments that have minimal side effects and little to no abuse/addiction liability. Research supported by this FOA must include rigorous validation studi...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 19, 2018 Category: Research Source Type: funding

Addressing Opioid Use Disorder in Pregnant Women and New Moms
A prize competition to support innovative solutions to improve access to quality health care, including substance use disorder treatment, recovery, and support services for pregnant women with opioid use disorders, their infants, and families, especially those in rural and geographically isolated areas. Geographic coverage: Nationwide -- Health Resources and Services Administration, U.S. Department of Health and Human Services (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - September 19, 2018 Category: American Health Source Type: funding

Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)
The purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and validation of novel therapeutic targets to facilitate the development of pain therapeutics. Specifically, the focus of this FOA is on the basic science discovery of targets in the peripheral nervous system, central nervous system, immune system or other tissues in the body that can be used to develop treatments that have minimal side effects and little to no abuse/addiction liability. Research supported by this FOA must include rigorous validation studies to demonstrate the robustness of the target as a pain treatment target. This wi...
Source: NIDDK Funding Opportunities - September 19, 2018 Category: Endocrinology Source Type: funding

NIH Policies to Address Sexual and Gender Harassment in NIH-supported Extramural Research
Several months ago, we learned in the press that an NIH-supported investigator was banned from his university campus pending an ongoing investigation into allegations of sexual misconduct.  The institution, which was the recipient of the awards in which this investigator was designated as principal investigator (PI), had not informed us of this situation.  Once aware, we contacted senior institutional officials to discuss the need to ensure the effective stewardship of the award under these circumstances. We requested that the institution provide us with alternative plans for conducting the research given that this indiv...
Source: NIH Extramural Nexus - September 17, 2018 Category: Research Authors: Mike Lauer Tags: blog Open Mike Compliance Grants policy Sexual Harassment Source Type: funding

Funding Longevity by Gender among NIH-Supported Investigators
For nearly 10 years, more women than men received PhDs in the biomedical sciences, yet women are still underrepresented at every subsequent stage of academic advancement.  In 2015, for example, women earned 53% of PhDs, but they comprised only 48% of post-doctoral fellows, 44% of assistant professors, and 35% of professors. To better understand what might be contributing to women’s underrepresentation in later stages of academia, Dr. Lisa Hechtman and her colleagues at the National Institute of General Medical Sciences (NIGMS) analyzed “funding longevity by gender” among funded NIH investigators.  Their analysis, r...
Source: NIH Extramural Nexus - September 7, 2018 Category: Research Authors: Mike Lauer Tags: blog Open Mike Biomedical Workforce Funding data Source Type: funding

Trends in Diversity within the NIH-funded Workforce
This study focused on the time period between 2009, when NIH first implemented new and early stage investigator policies, and 2016. When looking at the data by career-stage, we see that women, underrepresented racial minority, and Hispanic researchers comprise a higher percentage in both the ESI and NI groups compared to the experienced investigator (Exp) group (Table 1). This suggests these groups could be disproportionately affected if resources for new and early-stage investigators decline. However, these data also highlight an opportunity for NIH to enhance the diversity of the biomedical workforce by increasing suppo...
Source: NIH Extramural Nexus - August 7, 2018 Category: Research Authors: Mike Lauer Tags: blog Open Mike Uncategorized Biomedical Workforce Diversity funding rate NGRI Source Type: funding