The South-East Asian Transgender Health Cohort
Conditions:   HIV;   STIs;   HCV Intervention:   Sponsors:   Institute of HIV Research and Innovation Foundation, Thailand;   amfAR, The Foundation for AIDS Research Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 12, 2022 Category: Research Source Type: clinical trials

The South-East Asian Transgender Health Cohort
Conditions:   HIV;   STIs;   HCV Intervention:   Sponsors:   Institute of HIV Research and Innovation Foundation, Thailand;   The US NIH through the International Epidemiology Databases to Evaluate AIDS (IeDEA);   IeDEA Asia-Pacific (U01AI069907;   amfAR, The Foundation for AIDS Research Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 12, 2022 Category: Research Source Type: clinical trials

Protocol for an attention-matched randomized controlled trial of 2GETHER: a relationship education and HIV prevention program for young male couples
Discussion2GETHER is innovative in that it places an equal emphasis on relationship skill building and HIV prevention. Thus, the program has the potential to impact numerous health-related outcomes. Despite challenges related to the recruitment of couples and the COVID-19 pandemic, we were able to enroll a robust sample of young male couples with sufficient power to detect effects on study outcomes.Trial registrationClinicalTrials.govNCT03186534. (Source: Trials)
Source: Trials - June 20, 2022 Category: Research Source Type: clinical trials

Doxycycline post-exposure prophylaxis for prevention of sexually transmitted infections among Kenyan women using HIV pre-exposure prophylaxis: study protocol for an open-label randomized trial
DiscussionThe results of this trial may have immediate implications for the global epidemic of STIs and sexual health. If effective, dPEP could put STI prevention into women ’s hands. While dPEP may be able to prevent STIs, it carries important risks that could counter its benefits; global debate about the balance of these potential risks and benefits requires data to inform policy and implementation and our study aims to fill this gap.Trial registrationClinicalTrials.govNCT04050540. (Source: Trials)
Source: Trials - June 16, 2022 Category: Research Source Type: clinical trials

Health Information and Monitoring of Sexually Transmitted Infections (SIM study): a single-center, parallel, three-arm randomized controlled trial protocol for enhancing adherence to syphilis treatment and follow-up
ConclusionIf we find differences in effectiveness, a major change in the conventional approach for this patient population may be needed, potentially affecting current Brazilian health policy strategies.Trial registrationNTC04753125. Version 1 of protocol 1/09/2020. (Source: Trials)
Source: Trials - May 26, 2022 Category: Research Source Type: clinical trials

Sexually transmitted infection screening to prevent adverse birth and newborn outcomes: study protocol for a randomized-controlled hybrid-effectiveness trial
DiscussionThis trial is the first RCT designed to identify optimal, cost-effective screening strategies that decrease the burden of STIs during pregnancy and reduce adverse birth outcomes. Demonstrating the impact of diagnostic screening and treatment, compared to syndromic management, on birth outcomes will provide critical evidence to inform changes to WHO guidelines for syndromic management of STIs during pregnancy.Trial registrationClinicalTrials.govNCT04446611. Registered on 25 June 2020. (Source: Trials)
Source: Trials - May 24, 2022 Category: Research Source Type: clinical trials