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Common Features Between Stroke Following Varicella in Children and Stroke Following Herpes Zoster in Adults : Varicella-Zoster Virus in Trigeminal Ganglion
Curr Top Microbiol Immunol. 2021 Jul 6. doi: 10.1007/82_2021_236. Online ahead of print.ABSTRACTThe cerebral arteries are innervated by afferent fibers from the trigeminal ganglia. Varicella-zoster virus (VZV) frequently resides in the trigeminal ganglion. Reports of arterial ischemic stroke due to VZV cerebral vasculopathy in adults after herpes zoster have been described for decades. Reports of arterial ischemic stroke due to post-varicella cerebral arteriopathy in children have also been described for decades. One rationale for this review has been post-licensure studies that have shown an apparent protective effect fro...
Source: Current Topics in Microbiology and Immunology - July 5, 2021 Category: Microbiology Authors: Charles Grose Amir Shaban Heather J Fullerton Source Type: research

Varicella-zoster virus: molecular controls of cell fusion-dependent pathogenesis.
Abstract Varicella-zoster virus (VZV) is the causative agent of chicken pox (varicella) and shingles (zoster). Although considered benign diseases, both varicella and zoster can cause complications. Zoster is painful and can lead to post herpetic neuralgia. VZV has also been linked to stroke, related to giant cell arteritis in some cases. Vaccines are available but the attenuated vaccine is not recommended in immunocompromised individuals and the efficacy of the glycoprotein E (gE) based subunit vaccine has not been evaluated for the prevention of varicella. A hallmark of VZV pathology is the formation of multinuc...
Source: Biochemical Society Transactions - December 1, 2020 Category: Biochemistry Authors: Oliver SL, Zhou M, Arvin AM Tags: Biochem Soc Trans Source Type: research

Shingles Vaccine Linked to Lower Stroke Risk Shingles Vaccine Linked to Lower Stroke Risk
New evidence suggests the Zoster Vaccine Live — administered to prevent shingles — could also reduce the risk of stroke in older adults.Medscape Medical News
Source: Medscape Allergy Headlines - February 17, 2020 Category: Allergy & Immunology Tags: Neurology & Neurosurgery News Source Type: news

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