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Dabigatran - metabolism, pharmacologic properties and drug interactions.
Abstract The superiority of dabigatran has been well proven in the standard dosing regimen in prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF) and extended venous thromboembolism (VTE) treatment. Dabigatran, an anticoagulant with a good safety profile, reduces intracranial bleeding in patients with atrial fibrillation and decreases major and clinically relevant non-major bleeding in acute VTE treatment. However, several important clinical issues are not fully covered by currently available directions with regard to dabigatran administration. The prominat one is re...
Source: Current Drug Metabolism - April 26, 2017 Category: Drugs & Pharmacology Authors: Antonijevic N, Zivkovic I, Jovanovic L, Matic D, Kocica M, Mrdovic I, Kanjuh V, Culafic M Tags: Curr Drug Metab Source Type: research