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Source: Neurology
Therapy: Chemotherapy
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Total 18 results found since Jan 2013.
Real Eyes Realize Real Lies (P1.148)
Conclusions:In this case, CT Perfusion scanning was used to disprove vascular etiology and ultimately led to the appropriate diagnosis through further diagnostic testing.Disclosure: Dr. E-Ghanmh has nothing to disclose. Dr. Niazi has nothing to disclose. Dr. Ermak has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: El-Ghanem, M., Niazi, M., Ermak, D. Tags: General Neurology: The Eyes Have It and White Matter Matters Source Type: research
Stroke like migraine attacks after radiation therapy (SMART) syndrome a case series of three patients (P6.179)
Conclusions:Our patients represent the first case series of SMART syndrome in a single institution. Our cases share similarities to the prior reports in the literature and highlights the clinical and MRI triad of acute onset headaches, neurological deficits and MRI findings of transient contrast enhancement of the cortex with white matter sparing in a previous radiation field.Disclosure: Dr. rauf has nothing to disclose. Dr. Boulter has nothing to disclose. Dr. Imitola has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Rauf, Y., Boulter, D., Imitola, J. Tags: Neurologic Complications of Cancer Source Type: research
Neurologic manifestations of geriatric patients with cancer (P6.188)
Conclusions:Neurologic manifestations are reported in about 40% of patients with cancer, approximately half of living patients with cancer are over 65 years of age, this increase merits the medical and related personnel to be prepared and recognize, diagnose and treat this highly morbid conditions. Neurologic manifestations and diagnoses in patients with cancer are different in the elderly and should be treated individually; the present work offers information regarding clinical symptoms and neurologic diagnoses in this population.Disclosure: Dr. Cacho Diaz has nothing to disclose. Dr. Lorenzana-Mendoza has nothing to disc...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Diaz, B. C., Lorenzana-Mendoza, N., Soto, G. R., Gomez, A. H. Tags: Neurologic Complications of Cancer Source Type: research
Stroke-like migraine attacks in long term survivors of high grade glioma. (P1.174)
Conclusions:Stroke-like migraine attacks are difficult to treat and the pathophysiology is unknown. With more sophisticated imaging techniques, a better understanding of this phenomenon will aid in the treatment and prophylaxis of the syndrome with a goal of improving quality of life for this small but slowly growing population.Disclosure: Dr. New has nothing to disclose. Dr. Mirza has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: New, P., Mirza, H. Tags: Neuro-oncology: Gliomas I Source Type: research
Tumor Treating Fields (TTF) with Triple Chemotherapy for Recurrent Glioblastoma (P1.177)
Conclusions:Therapies with TTF plus TBC demonstrates superior OS benefit for recurrent GBM with moderate, but manageable side effects. A prospective study of TTF plus TBC for recurrent GBM is warranted.Study Supported by: Dr. Marnie Rose FoundationDisclosure: Dr. Zhu has received personal compensation for activities with Novocure, and Prime Oncology. Dr. Zhu has received research support from Novocure, Inc., Five Prime Therapeutics, Immuno-Cellular Inc., DEKK-TEC. Dr. Lu has nothing to disclose. Dr. Rao has nothing to disclose. Dr. Zhu has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Zhu, J.-J., Lu, G., Rao, M., Zhu, P. Tags: Neuro-oncology: Gliomas I Source Type: research
Vestibulocochlear nerve dysfunction as initial manifestation of Waldenstrom Macroglobulinemia (P5.193)
Conclusions:Clinical findings from this case demonstrated early vascular complications of multiple peripheral neurosensory systems secondary to WM-related hyperviscosity. Early recognition of symptoms through detailed history taking and neurological examination is necessary for a correct diagnosis and better outcome.Disclosure: Dr. Humayun has nothing to disclose. Dr. Panjwani has nothing to disclose. Dr. Li has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Humayun, M., Panjwani, S., Li, H. Tags: Neuro-ophthalmology/Neuro-otology I Source Type: research
Acute Ischemic Stroke as a Presenting Feature of Multiple Myeloma (P3.279)
Conclusions:Stroke is a leading and preventable cause of disability in the US adult population. The majority of strokes are due to atherosclerotic vascular or cardioembolic disease. Understanding the diagnostic work up of stroke and recognizing rare etiologies like MM is important for stroke prevention. This brings to light the importance of recognizing stroke as an initial presenting feature of multiple myeloma and of multiple myeloma as an important treatable etiology of stroke.Disclosure: Dr. Chung has nothing to disclose. Dr. Ramamoorthy has nothing to disclose. Dr. Kar has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Chung, S., Ramamoorthy, R., Kar, J. Tags: Cerebrovascular Disease Case Reports II Source Type: research
Atypical PRES in Systemic Hodgkins Lymphoma Post R-ABVD Chemotherapy (P4.341)
Conclusions: Leptomeningeal and Corpus Callosum involvement in a patient with systemic lymphoma should not only raise suspicion for CNS spread but also atypical PRES. Disclosure: Dr. Shaikh has nothing to disclose. Dr. Wong has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Shaikh, N., Wong, C. Tags: Cerebrovascular Case Reports Source Type: research
Clinical Reasoning: A 68-year-old man with a history of lung cancer presenting with right-sided weakness and aphasia
A 68-year-old man with paroxysmal atrial fibrillation on warfarin, left subclavian thrombosis treated with carotid-subclavian bypass, and lung adenocarcinoma treated with pneumonectomy, chemotherapy, and prophylactic cranial irradiation and in remission since 1987 was admitted to our neurocritical care unit with acute onset of right-sided weakness, expressive aphasia, and lethargy. On admission his temperature was 101.7°F, and initial blood pressure was 140/60 mm Hg. There was no nuchal rigidity. He was alert and mute with impaired comprehension. He had left gaze preference. Vision was impaired in the right field. Ther...
Source: Neurology - October 5, 2015 Category: Neurology Authors: Gupta, A., Etherton, M. R., McKee, K., Baker, J. M., Izzy, S., Feske, S. K. Tags: All Cerebrovascular disease/Stroke, Radiation therapy-tumor, All Epilepsy/Seizures RESIDENT AND FELLOW SECTION Source Type: research
Effects of Acupuncture on Neuropathic Pain: A Systematic Review and Meta-analysis (P3.306)
CONCLUSIONS: The majority of trials demonstrate a positive effect of acupuncture over control condition in the treatment of neuropathy. Further more rigorously designed studies are needed to better characterize this effect.Disclosure: Dr. Dimitrova has nothing to disclose. Dr. Murchison has received research support from the National Institute for Neurological Disorders and Stroke. Dr. Oken has received personal compensation for activities with Dr. Willmar Schwabe Pharmaceuticals as a speaker.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Dimitrova, A., Murchison, C., Oken, B. Tags: Pain and Palliative Care Source Type: research
Methotrexate Encephalopathy as a Cause of Alternating Hemiplegia (P3.143)
CONCLUSIONS: Transient neurologic dysfunction with reversible MRI abnormality is a recognized consequence of intrathecal methotrexate chemotherapy in childhood ALL. Patients present with dramatic fluctuating neurologic symptoms with associated MRI changes and may be mistaken for stroke or a seizure disorder. Once the syndrome is recognized patients typically recover with supportive management and rehabilitation.Disclosure: Dr. Sullivan has nothing to disclose. Dr. Quealy has nothing to disclose. Dr. Olsevskaite has nothing to disclose. Dr. MacEneaney has nothing to disclose. Dr. Ryan has nothing to disclose. Dr. O'Toole ha...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Sullivan, C., Quealy, J., Olsevskaite, J., MacEneaney, P., Ryan, C., O'Toole, O. Tags: Neuro-oncology: CNS Lymphoma and Other Hematologic Malignancies Source Type: research
Hypertensive crisis: Reversible edema in leukoencephalopathy, retinopathy, now myelopathy?
The definition of the clinicoradiologic syndrome posterior reversible leukoencephalopathy syndrome (PRES) has been stretched over the last decade.1 Many regard PRES as a final common denominator for various cerebral insults, without a single etiopathogenic trigger.1,2 The hallmark of classic PRES is hydrostatic pressure breakthrough causing cerebral vasogenic edema, commonly coupled with a history of refractory hypertension, ictal surge in blood pressure (BP), and a concomitant systemic inflammatory or uremic process.1 High BP may be absent in PRES if there is renal failure; infection or any systemic inflammatory response ...
Source: Neurology - November 24, 2014 Category: Neurology Authors: Kapinos, G., Sanelli, P. C. Tags: Other cerebrovascular disease/ Stroke EDITORIALS Source Type: research
Epilepsy and Cancer: Ancient Problem in a Top Mortality Illness (P3.313)
CONCLUSIONS: Seizures in patients with cancer is a frequent comorbid condition with a high mortality rate, further studies are required to study the efficacy and security of AED and other forms of treatment.Study Supported by: NoneDisclosure: Dr. Cacho Diaz has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Cacho Diaz, B. Tags: Neurologic Complications of Cancer Source Type: research
Cerebral microbleeding in varicella-zoster viral meningitis: An early sign of vasculopathy?
A 75-year-old man undergoing chemotherapy for prostate cancer for 3 months presented with headache after having blisters in his left ear canal and auricle. His body temperature at presentation was 38°C. Neurologic examination revealed nuchal stiffness and left peripheral facial palsy. We also noted leukocytopenia (2,000/µL) and elevated serum C-reactive protein (8.51 mg/dL). CSF analysis showed no erythrocytes, elevated leukocytes (640/µL; 3% monocytes, 97% neutrophils), an increased protein level (473 mg/dL), and slightly decreased glucose level (51 mg/dL, serum glucose 120 mg/dL). Brain MRI and magnetic r...
Source: Neurology - March 3, 2014 Category: Neurology Authors: Ohtomo, R., Shirota, Y., Iwata, A., Shimizu, J., Tsuji, S. Tags: MRI, Other cerebrovascular disease/ Stroke, Vasculitis, Viral infections CLINICAL/SCIENTIFIC NOTES Source Type: research
Teaching NeuroImages: Methotrexate neurotoxicity: Resolution and evolution of MRI changes within 48 hours
A 13-year-old girl presented with acute-onset right hemiparesis involving the face, arm, and leg equally. She was receiving weekly intrathecal methotrexate (last dose 6 days prior) for recently diagnosed acute lymphocytic leukemia. Brain MRI (figure 1) showed diffusion restriction in the left centrum semiovale with reduced apparent diffusion coefficient. Her hemiparesis resolved within 24 hours but 2 hours later, she developed 12-hour left hemiparesis involving face, upper limb, and dysarthria. Follow-up neurologic examination was normal. Repeat MRI (figure 2) 44 hours after the original MRI showed acute right centrum semi...
Source: Neurology - September 2, 2013 Category: Neurology Authors: Kanaan, S., Poddar, K., Ng, Y.-T. Tags: Childhood stroke, MRI, DWI, Chemotherapy-tumor, All Pediatric RESIDENT AND FELLOW SECTION Source Type: research
