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Nonbacterial Thrombotic Endocarditis Due to Primary Gallbladder Malignancy with Recurrent Stroke Despite Anticoagulation: Case Report and Literature Review
AbstractNonbacterial thrombotic endocarditis (NBTE) associated with malignancy is rare; its infrequency and similarity to other diagnoses make it a significant diagnostic challenge. A 63-year-old woman on rivaroxaban for prior deep vein thrombosis presented with left upper extremity weakness and left facial droop with imaging demonstrating multiple strokes. Echocardiograms revealed mitral and aortic valve vegetations. The patient was switched to apixaban and started on vancomycin and ceftriaxone for presumed culture-negative endocarditis. Despite continuing apixaban, her hospital course was complicated by new acute embolic...
Source: Journal of General Internal Medicine - July 15, 2019 Category: Internal Medicine Source Type: research

Black pleural effusion as the presenting feature of lung cancer.
Conclusion: In the present case, the black stain most likely results from intrapleural haemolysis following haemorrhage. Pleural fluid bilirubin may be useful in evaluating pleural effusion, especially if black.
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Fernandes, V., Alfaro, T. M., Cruz, C., Cordeiro, C. R. Tags: Clinical Problems Source Type: research

Cervical adenocarcinoma generator of procoagulant status and ischemic stroke.
We present the case of a 44-years-old patient undergoing early menopause, who was diagnosed with cervical tumor of the serous adenocarcinoma type. The patient underwent external radiotherapy, and, in the seventh day of treatment, she suffered a frontal-temporal-parietal ischemic stroke with left hemiplegia. The blood testing highlighted procoagulant products (double fibrinogen compared to normal values, deficit of antithrombin and a high number of thrombocytes). The patient received neurological and rehabilitation treatment, at first with Heparin, followed by the administration of an antiaggregant. During this treatment, t...
Source: Romanian Journal of Morphology and Embryology - March 23, 2018 Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research

Severe Symptoms, but a Truly Treatable Disease
​BY NOURA MAHDI; DARRON LEWIS; JEREMY OSBORNE; & AHMED RAZIUDDIN, MDA 73-year-old man was brought to the emergency department from his nursing home for rectal bleeding and anemia. The patient mentioned he had had episodes of bright red rectal bleeding and constipation for a few months. A colonoscopy had been done prior to the visit, which revealed a large intestine tumor and biopsy confirming adenocarcinoma. He was awaiting an appointment with his surgeon.The patient reported bloody rectal leakage, and a CBC done at the nursing home showed a hemoglobin level of 7.2. He also complained of dyspnea but denied any other ...
Source: The Case Files - March 20, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: research

A Case of Posterior Reversible Encephalopathy Syndrome Induced by Cisplatin/Pemetrexed Chemotherapy for Lung Cancer
This report presents the case of a 60-year-old woman who was diagnosed with stage IV lung adenocarcinoma with asymptomatic brain metastases and commenced chemotherapy with cisplatin/pemetrexed (CDDP/Pem). She experienced tonic-clonic convulsions on day 9 of the first cycle, which were accompanied by increased blood pressure (173/69 mm Hg) and headache. Therefore, brain MRI was performed to check for stroke or progression of brain metastatic foci. T2-weighted, FLAIR, and ADC map images showed high-intensity areas in the subcortical region of the bilateral parieto-occipital lobes, leading to a diagnosis of posterior reversib...
Source: Case Reports in Oncology - March 9, 2017 Category: Cancer & Oncology Source Type: research

Clinical Reasoning: A 68-year-old man with a history of lung cancer presenting with right-sided weakness and aphasia
A 68-year-old man with paroxysmal atrial fibrillation on warfarin, left subclavian thrombosis treated with carotid-subclavian bypass, and lung adenocarcinoma treated with pneumonectomy, chemotherapy, and prophylactic cranial irradiation and in remission since 1987 was admitted to our neurocritical care unit with acute onset of right-sided weakness, expressive aphasia, and lethargy. On admission his temperature was 101.7°F, and initial blood pressure was 140/60 mm Hg. There was no nuchal rigidity. He was alert and mute with impaired comprehension. He had left gaze preference. Vision was impaired in the right field. Ther...
Source: Neurology - October 5, 2015 Category: Neurology Authors: Gupta, A., Etherton, M. R., McKee, K., Baker, J. M., Izzy, S., Feske, S. K. Tags: All Cerebrovascular disease/Stroke, Radiation therapy-tumor, All Epilepsy/Seizures RESIDENT AND FELLOW SECTION Source Type: research

P2-33-4 * lung cancer chemotherapy in patients undergoing daialysis
Conclusion: Chemotherapy for lung cancer patients undergoing dialysis were associated with severe hematological toxicity.It is urgent task to establish optimal cancer chemotherapy and management of adverse events.
Source: Annals of Oncology - October 19, 2014 Category: Cancer & Oncology Authors: Sato, K., Kuriyama, H., Sakamoto, H., Ebe, Y., Koike, T. Tags: Poster Session (Poster presentations categorized by each organ) Source Type: research

P2-33-4 * lung cancer chemotherapy in patients undergoing daialysis
Conclusion: Chemotherapy for lung cancer patients undergoing dialysis were associated with severe hematological toxicity.It is urgent task to establish optimal cancer chemotherapy and management of adverse events.
Source: Annals of Oncology - October 19, 2014 Category: Cancer & Oncology Authors: Sato, K., Kuriyama, H., Sakamoto, H., Ebe, Y., Koike, T. Tags: Poster Session (Poster presentations categorized by each organ) Source Type: research

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