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Specialty: Veterinary Research
Drug: Gleevec
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Total 1 results found since Jan 2013.
Therapeutic effect of low-dose imatinib on pulmonary arterial hypertension in dogs.
Abstract
This was a pilot study to determine the effectiveness of low-dose imatinib therapy for hemodynamic disturbances, including pulmonary arterial hypertension (PAH), and clinical manifestations caused by chronic heart failure in dogs. Six client-owned dogs with PAH were administered imatinib mesylate orally, 3 mg/kg body weight q24h, for 30 d. Physical examination, blood biochemical tests, radiography, and Doppler echocardiography were performed prior to imatinib administration and again 30 days after administration. Clinical scores were significantly reduced after imatinib treatment. Systolic pulmonary arter...
Source: The Canadian Veterinary Journal - March 1, 2013 Category: Veterinary Research Authors: Arita S, Arita N, Hikasa Y Tags: Can Vet J Source Type: research
