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Effects of Hypoxia-Inducible Factor 1 (HIF-1) Signaling Pathway on Acute Ischemic Stroke
CONCLUSION: By detecting the expression changes of Hesl+factor VII in the ischemic area, the results show that ischemia and hypoxia activate the HIF-1, making the HIF-l the main regulatory pathway in the process of angiogenesis after ischemia.PMID:36276989 | PMC:PMC9586786 | DOI:10.1155/2022/1860925
Source: Computational and Mathematical Methods in Medicine - October 24, 2022 Category: Statistics Authors: Guoliang Li Liang Tao Hui Wu Source Type: research

Related Factors of Cerebral Hemorrhage after Cerebral Infarction and the Effect of Atorvastatin Combined with Intensive Nursing Care
CONCLUSION: Patients with hypertension, large infarction lesions, high NIHSS score at admission, atrial fibrillation, and small artery occlusion cerebral infarction can increase the risk of bleeding transformation in patients with cerebral infarction. For patients with bleeding transformation, atorvastatin calcium tablets combined with early intensive nursing intervention has a certain value for improving the prognosis of patients.PMID:35959354 | PMC:PMC9357761 | DOI:10.1155/2022/9546006
Source: Computational and Mathematical Methods in Medicine - August 12, 2022 Category: Statistics Authors: Qian Yang Yuedong Yang Xiaoting Li Source Type: research

Effect of Optimized Emergency Care on Treatment Rate and Prognosis of Elderly Patients with Acute Stroke in Emergency Department: A Systematic Review and Meta-Analysis
CONCLUSION: Optimizing the emergency care process can effectively improve the emergency rate and prognosis of elderly patients with acute stroke in emergency department; however, further research with higher methodological quality and longer intervention time are needed to verify later.PMID:35928978 | PMC:PMC9345692 | DOI:10.1155/2022/5841978
Source: Computational and Mathematical Methods in Medicine - August 5, 2022 Category: Statistics Authors: Xia Liang Yanhong Yu Source Type: research

Clinical Features of Acute Coronary Syndrome in Patients with Coronary Heart Disease and Its Correlation with Tumour Necrosis Factor in Cardiology
Comput Math Methods Med. 2022 Jun 30;2022:3439768. doi: 10.1155/2022/3439768. eCollection 2022.ABSTRACTTumour necrosis factor (TNF) levels are higher in patients who have experienced an acute ischemic stroke. Greater levels of TNF may not be linked to an increased risk of recurrent coronary events in the stable phase after myocardial ischemia (MI). Coronary atheroma is connected to endothelial and smooth muscle cells, as well as macrophages that emit the multifunctional cytokine tumour necrosis factor (TNF). Transplanted tumours become more vulnerable when TNF-α was first recognized to have a function in hemorrhagic necro...
Source: Computational and Mathematical Methods in Medicine - July 11, 2022 Category: Statistics Authors: Run Guo Tingting Wu Nan Zheng Yanfang Wan Jun Wang Source Type: research

Effect of Acupuncture and Rehabilitation Therapy on the Recovery of Neurological Function and Prognosis of Stroke Patients
CONCLUSION: Acupuncture of traditional Chinese medicine combined with rehabilitation therapy has outstanding effects in stroke treatment and can effectively improve the neurological function, prognosis, and quality of life of patients, which is worthy of clinical promotion.PMID:35242206 | PMC:PMC8888046 | DOI:10.1155/2022/4581248
Source: Computational and Mathematical Methods in Medicine - March 4, 2022 Category: Statistics Authors: Lanping Fu Fei Wang Zhiyi Ma Jin Zhang Wuzhong Xiong Le Wang Source Type: research

A Semantic Analysis and Community Detection-Based Artificial Intelligence Model for Core Herb Discovery from the Literature: Taking Chronic Glomerulonephritis Treatment as a Case Study.
Authors: Zhang Y, Liu Y, Zhu J, Zhai S, Jin R, Wen C Abstract The Traditional Chinese Medicine (TCM) formula is the main treatment method of TCM. A formula often contains multiple herbs where core herbs play a critical therapeutic effect for treating diseases. It is of great significance to find out the core herbs in formulae for providing evidences and references for the clinical application of Chinese herbs and formulae. In this paper, we propose a core herb discovery model CHDSC based on semantic analysis and community detection to discover the core herbs for treating a certain disease from large-scale literatur...
Source: Computational and Mathematical Methods in Medicine - September 23, 2020 Category: Statistics Tags: Comput Math Methods Med Source Type: research