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Active targeting towards and inside the brain based on nanoparticles: A Review.
Abstract Treatment of neurological diseases using systemic and non-surgical techniques presents a significant challenge in medicine. This challenge is chiefly associated with the condensation and coherence of the brain tissue. The coherence structure of the brain is due to the presence of the blood brain barrier (BBB), which consists of a continuous layer of capillary endothelial cells. The BBB prevents most drugs from entering the brain tissue and is highly selective, permitting only metabolic substances and nutrients to pass through. Although this challenge has caused difficulties for the treatment of neurologic...
Source: Current Pharmaceutical Biotechnology - December 1, 2019 Category: Biotechnology Authors: Rabiei M, Kashanian S, Samavati SS, Jamasb S, McInnes SJP Tags: Curr Pharm Biotechnol Source Type: research