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Sensors, Vol. 21, Pages 831: Affimer-Based Europium Chelates Allow Sensitive Optical Biosensing in a Range of Human Disease Biomarkers
Paul Millner The protein biomarker measurement has been well-established using ELISA (enzyme-linked immunosorbent assay), which offers good sensitivity and specificity, but remains slow and expensive. Certain clinical conditions, where rapid measurement or immediate confirmation of a biomarker is paramount for treatment, necessitate more rapid analysis. Biosensors offer the prospect of reagent-less, processing-free measurements at the patient’s bedside. Here, we report a platform for biosensing based on chelated Eu3+ against a range of proteins including biomarkers of cardiac injury (human myoglobin), st...
Source: Sensors - January 27, 2021 Category: Biotechnology Authors: Eiman Al-Enezi Alexandre Vakurov Amy Eades Mingyu Ding Gin Jose Sikha Saha Paul Millner Tags: Article Source Type: research