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Specialty: Cardiology
Source: International Journal of Cardiology

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Total 880 results found since Jan 2013.

Percutaneous left atrial appendage closure versus oral anticoagulant: A bird in the hand is worth two in the bush?
Since the technology of percutaneous left atrial closure (LAAC) was developed to prevent thromboembolic events in non-valvular atrial fibrillation (AF) patients, debate continues over its risks and benefits. Some support LAAC as it significantly reduces bleeding and all-cause mortality and is non-inferior, if not superior, to warfarin in terms of stroke prevention [1,2]; however, others question the data retrieved from the LAAC-related trials and argue the efficacy and safety of LAAC devices. The more the device is used, the stronger the voice from both camps.
Source: International Journal of Cardiology - November 30, 2017 Category: Cardiology Authors: Rong Bai Tags: Editorial Source Type: research

Yield of atrial fibrillation detection with Textile Wearable Holter from the acute phase of stroke: Pilot study of Crypto-AF registry
We describe the feasibility of monitoring with a Textile Wearable Holter (TWH) in patients included in Crypto AF registry.
Source: International Journal of Cardiology - October 22, 2017 Category: Cardiology Authors: Jorge Pagola, Jesus Juega, Jaume Francisco-Pascual, Angel Moya, Mireia Sanchis, Alejandro Bustamante, Anna Penalba, Maria Usero, Elisa Cortijo, Juan F. Arenillas, Ana I. Calleja, Maria Sandin-Fuentes, Jeronimo Rubio, Fernando Mancha, Irene Escudero-Martin Source Type: research

Physician deaths from overwork should arouse greater attention in China
With great interest we read Dr. Wong's paper published in November 2016 in International Journal of Cardiology [1]. They concluded that sleep deprivation or overwork could be a proarrhythmic factor for idiopathic ventricular fibrillation. Besides, some researchers also found that overwork has been associated with an increase in the risk of heart disease, stroke, medical accidents and errors, threatened abortion and preterm birth, as well as a decrease in quality of patient care [2,3].
Source: International Journal of Cardiology - October 18, 2017 Category: Cardiology Authors: Yan-Fei Shen, Xiang-Yong Hao, Tian-Kang Guo Tags: Letter to the Editor Source Type: research

Epigenetics and cardiovascular regenerative medicine in the elderly
Cardiovascular disease (CVD) is a recognized age-dependent condition whose incidence is set to increase due to the gradual aging of the population. Moreover, ischemic cardiovascular diseases (i.e. stroke, myocardial infarction, critical limb ischemia) requiring blood vessel growth are associated with a worse outcome in elderly patients. Therefore, understanding the molecular cues regulating the vascular repair process is of paramount importance to prevent undesirable cardiovascular complications in this setting.
Source: International Journal of Cardiology - September 25, 2017 Category: Cardiology Authors: Sarah Costantino, Giovanni G. Camici, Shafeeq Ahmed Mohammed, Massimo Volpe, Thomas F. L üscher, Francesco Paneni Tags: Review Source Type: research

Impact of atrial arrhythmias on outcome in adults with congenital heart disease
Adults with congenital heart disease (ACHD) are affected by atrial arrhythmias (AA). To elucidate the impact of AA on prognosis, we aimed to determine the impact of AA on death, heart failure and stroke in ACHD patients in a prospective nationwide clinical registry.
Source: International Journal of Cardiology - September 22, 2017 Category: Cardiology Authors: H. Yang, J.M. Kuijpers, J.R. de Groot, T.C. Konings, A. van Dijk, G.Tj. Sieswerda, M.C. Post, B.J.M. Mulder, B.J. Bouma Tags: Short communication Source Type: research

Clinical conundrums in antithrombotic therapy management: A Delphi Consensus panel
Anticoagulants are recommended for the prevention of stroke/systemic embolism for most patients with atrial fibrillation (AF) and for the treatment of patients with venous thromboembolism (VTE). Regulatory-driven randomized trials, however, typically exclude extreme patient scenarios involving, for instance, severe bleeding, ischaemic risk, frailty or renal impairment, despite their common occurrence in clinical practice. Uncertainty in the management of such cases leads to a high degree of variability in therapeutic approaches.
Source: International Journal of Cardiology - September 18, 2017 Category: Cardiology Authors: Paolo Colonna, Felicita Andreotti, Walter Ageno, Vittorio Pengo, Niccol ò Marchionni Source Type: research

Impact of stroke volume assessment by integrating multi-detector computed tomography and Doppler data on the classification of aortic stenosis
The prevalence of low flow low gradient (LFLG) severe aortic stenosis (AS) may be overrated due to underestimation of stroke volume in two-dimensional (2D) echocardiography. The implications of 3D imaging on stroke volume calculation for AS classification have not been elucidated. Integrating multi-detector computed tomography (MDCT) and Doppler data may improve diagnostic accuracy in patients with LFLG AS.
Source: International Journal of Cardiology - September 1, 2017 Category: Cardiology Authors: Barbara E. St ähli, Thomas Stadler, Erik W. Holy, Thi Dan Linh Nguyen-Kim, Lisa Hoffelner, Ladina Erhart, Slayman Obeid, Markus Niemann, Rolf Jenni, Sandra Hamada, Robert Manka, Thomas F. Lüscher, Francesco Maisano, Fabian Nietlispach, Thomas Frauenfeld Source Type: research

Left Atrial Appendage Closure for Prevention of Death, Stroke, and Bleeding in Patients with Nonvalvular Atrial Fibrillation
Nonvalvular atrial fibrillation (AF) is the most frequent arrhythmia with a prevalence of 1% - 2% in the general population. Its prevalence increases with age and its diagnosis benefits of improvement and simplification of technologies for its detection. Today, AF affects approximately 7% of individuals age>65years and 15% –20% of octogenarians. Due to stasis and activation of coagulation in a fibrillating atrium, patients are at increased risk of thromboembolism, in particular ischemic stroke, with an overall stroke risk of 5% per year.
Source: International Journal of Cardiology - August 26, 2017 Category: Cardiology Authors: Steffen Gloekler, Jacqueline Saw, Konstantinos C. Koskinas, Werner Jung, Fabian Nietlispach, Bernhard Meier Source Type: research

Excessive atrial ectopic activity as an independent risk factor for ischemic stroke
Excessive atrial ectopic activity (EAEA) has been related with an increased risk of atrial fibrillation (AF) and stroke but different cutoff values have been used. We aimed to determine the association between EAEA and stroke, AF and overall death.
Source: International Journal of Cardiology - August 26, 2017 Category: Cardiology Authors: Rita Marinheiro, Leonor Parreira, Pedro Amador, Catarina S á, Tatiana Duarte, Rui Caria Source Type: research

Use of statins and adverse outcomes in patients with atrial fibrillation: An analysis from the EURObservational Research Programme Atrial Fibrillation (EORP-AF) general registry pilot phase
Despite oral anticoagulation being highly effective in reducing stroke and thromboembolism, patients with atrial fibrillation (AF) still have a significant residual excess in mortality risk. Additional management strategies are needed to reduce the mortality risk seen in AF patients.
Source: International Journal of Cardiology - August 25, 2017 Category: Cardiology Authors: Marco Proietti, C écile Laroche, Ole Nyvad, Maciej Haberka, Vassilios P. Vassilikos, Aldo P. Maggioni, Giuseppe Boriani, Gregory Y.H. Lip, EORP-AF Pilot Investigators Source Type: research

Looking for the gender equality
Coronary artery disease (CAD) is one of the major causes of morbidity and mortality worldwide, both in men and women [1]. In Europe, about 43% of all female deaths are caused by cardiovascular disease, in particular CAD and stroke [2]; the proportion of women over the fifth decade affected by CAD is estimated at about 32% [3].
Source: International Journal of Cardiology - August 5, 2017 Category: Cardiology Authors: M. Deidda, G. Mercuro Tags: Editorial Source Type: research

Targeting supraventricular ectopic complexes: Which approach should be used and how does it affect atrial fibrillation?
Atrial fibrillation (AF) represents a major global health burden due to its high prevalence and significant impact on morbidity and mortality [1]. In addition to anticoagulation to reduce the risk of stroke, AF management includes normalization of the ventricular response ( ‘rate control’) or restoration and maintenance of normal sinus rhythm (‘rhythm control’). Although several large clinical trials have shown that both rate- and rhythm-control strategies produce similar outcomes, rhythm control is often attempted in symptomatic patients [1].
Source: International Journal of Cardiology - August 5, 2017 Category: Cardiology Authors: Jordi Heijman, Dobromir Dobrev, Harry J.G.M. Crijns Tags: Editorial Source Type: research

Avoiding cerebrovascular events after TAVI: Need for an integrated approach
Over the past years, transcatheter aortic valve implantation (TAVI) has gradually become an alternative treatment strategy in patients with severe aortic valve stenosis (AVS) at high surgical risk and, more recently, also in intermediate-risk patients [1]. In this respect, while procedural success may be practically assured, complications, though heavily reduced, are still present and need to be carefully addressed in order to further improve clinical outcome. Among the major complications of TAVI, the occurrence of a stroke remains undoubtedly the most feared, associating with a striking rate of early mortality and major disability.
Source: International Journal of Cardiology - August 5, 2017 Category: Cardiology Authors: Anna Sonia Petronio, Riccardo Liga, Marco De Carlo Tags: Editorial Source Type: research

Dynamic balance of platelet reactivity in atrial fibrillation PARtially unravelled
The World Heart Federation recently launched a roadmap to reduce the substantial disease and healthcare burden associated with non-valvular atrial fibrillation (AF). AF is the most common and clinically significant form of cardiac arrhythmia, and independently associated with a 5-fold increased risk of ischemic stroke [1]. Thromboembolisms generally arise from structurally and electrically remodelled left atria exhibiting impaired contractility and blood stasis. Increased thrombogenicity may additionally predispose to both AF and stroke.
Source: International Journal of Cardiology - July 23, 2017 Category: Cardiology Authors: Anke C. Fender, Dobromir Dobrev Tags: Editorial Source Type: research

Increased arterial stiffness and haemorrhagic transformation in ischaemic stroke after thrombolysis: A new marker of risk for cerebrovascular events and complications
Essential hypertension is the most frequent cardiovascular risk factor in the general population, and its prevalence is even higher in specific subsets of high-risk individuals, such as elderly, patients with diabetes, coronary artery disease or stroke [1]. In view of the large prevalence and growing incidence, as well as in view of the strong and independent correlation between high blood pressure (BP) levels and increased risk of major cardiovascular and cerebrovascular complications, mostly including myocardial infarction, stroke, congestive heart failure and cardiovascular death [2], several studies have addressed the ...
Source: International Journal of Cardiology - July 23, 2017 Category: Cardiology Authors: Giuliano Tocci, Vivianne Presta Tags: Editorial Source Type: research