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The Effect of Anesthetic Type on Outcomes of Hip Fracture Surgery: A Nationwide Population-Based Study
Abstract: Hip fractures are a global public health problem. During surgery following hip fractures, both general and regional anesthesia are used, but which type of anesthesia offers a better outcome remains controversial. There has been little research evaluating different anesthetic types on mortality and readmission rates for hip fracture surgery using nationwide population-based data. We used nationwide population-based data to examine the effect of anesthetic type on mortality and readmission rates for hip fracture surgery. Retrospective observational study. General acute care hospitals throughout Taiwan. A total ...
Source: Medicine - April 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Long-term aspirin use and neovascular age-related macular degeneration: association or causation?
Commentary on: Liew G, Mitchell P, Wong TY, et al.. The association of aspirin use with age-related macular degeneration. JAMA Intern Med 2013;173:258–64. Context Aspirin is used by many for temporary pain relief, rheumatological conditions and where indicated, cardioprotection. However, recent findings from observational studies have raised the possibility that regular aspirin use may also increase the risk of some forms of age-related macular degeneration (AMD). Methods Liew and colleagues examined the relationship between long-term, low-dose aspirin use and risk of AMD in an Australian population-based cohort of 2...
Source: Evidence-Based Medicine - January 22, 2014 Category: Internal Medicine Authors: Christen, W. G. Tags: EBM Aetiology, Smoking and tobacco, Epidemiologic studies, Immunology (including allergy), Drugs: cardiovascular system, Pain (neurology), Stroke, Hypertension, Ophthalmology, Pain (palliative care), Pain (anaesthesia), Diabetes, Health education, Smoking Source Type: research

Single surgical procedure with general anaesthesia early in life is associated with subsequent impaired language development and cognitive function
Commentary on: Ing C, Dimaggio C, Whitehouse A, et al.. Long-term differences in language and cognitive function after childhood exposure to anesthesia. Pediatrics 2012;130:e476–85. Context Thus far, more than 250 studies in immature animals have demonstrated that exposure to commonly used anaesthetics produces neuronal cell death, alters brain development and may lead to neurocognitive impairment.1 2 Similarly, in humans, an association between learning disabilities and two or more anaesthetic exposures has been observed in some studies, as most recently reported in children under 2 years of age.3 Methods Ing a...
Source: Evidence-Based Medicine - July 5, 2013 Category: Internal Medicine Authors: Loepke, A. W. Tags: Rehabilitation medicine, Stroke, Developmental paediatrics, Child and adolescent psychiatry, Other anaesthesia Harm Source Type: research

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