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Review: In diabetes with multivessel or left main CAD, PCI increases death/MI/stroke combo compared with CABG.
PMID: 25775351 [PubMed - in process]
Source: Annals of Internal Medicine - March 17, 2015 Category: Internal Medicine Authors: Hlatky MA Tags: Ann Intern Med Source Type: research

Coronary Revascularization in Diabetic Patients: A Systematic Review and Bayesian Network Meta-analysis.
CONCLUSION: Coronary artery bypass grafting seems to be the preferred revascularization technique in diabetics, especially if long-term survival is anticipated. However, because of residual uncertainties and increased risk for stroke with CABG, clinical judgment is required when choosing a revascularization technique in patients with diabetes. PRIMARY FUNDING SOURCE: Fonds de recherche du Québec-Santé. PMID: 25402514 [PubMed - in process]
Source: Annals of Internal Medicine - November 18, 2014 Category: Internal Medicine Authors: Tu B, Rich B, Labos C, Brophy JM Tags: Ann Intern Med Source Type: research

The prognostic significance of declining health-related quality of life scores at 6 months after coronary artery bypass surgery
Conclusions: Deteriorating function and HRQoL-scores at 6 months as compared to baseline postoperatively predict later adverse cardiovascular events after CABG.
Source: QJM - April 25, 2014 Category: Internal Medicine Authors: Gunn, J. M., Lautamaki, A. K., Hirvonen, J., Kuttila, K. T. Tags: Original papers Source Type: research

Coronary revascularisation in patients with diabetes: a chance to be better
Commentary on: Farkouh ME, Domanski M, Sleeper LA, et al.. Strategies for multivessel revascularisation in patients with diabetes. N Engl J Med 2012;367:2375–84. Context In 2009, a pooled analysis of individual patient data from randomised clinical trials comparing percutaneous coronary interventions (PCI) with coronary artery bypass grafting (CABG) showed a survival benefit in favour of CABG.1 Techniques of both PCI and CABG evolved during the last decade with the use of drug-eluting stents (DES) and novel antiplatelet agents. Methods In the FREEDOM trial, patients with diabetes and multivessel coronary artery disea...
Source: Evidence-Based Medicine - November 21, 2013 Category: Internal Medicine Authors: Windecker, S., Stefanini, G. G. Tags: Epidemiologic studies, Drugs: cardiovascular system, Stroke, Interventional cardiology, Ischaemic heart disease Therapeutics Source Type: research

Prognostic implications of DPP‐4 inhibitor vs. sulfonylurea use on top of metformin in a real world setting – results of the 1 year follow‐up of the prospective DiaRegis registry
ConclusionsThe present results confirm prior randomised controlled trial results in patients with type 2 diabetes from real world clinical practice demonstrating that DPP4‐I on top of prior metformin monotherapy result in similar HbA1c reductions within 12 months but a significant reduction in hypoglycaemia compared with sulfonylurea added to metformin. The reduction in vascular events observed has to be verified in larger cohorts.
Source: International Journal of Clinical Practice - August 28, 2013 Category: Internal Medicine Authors: A. K. Gitt, P. Bramlage, C. Binz, M. Krekler, E. Deeg, D. Tschöpe Tags: Original Paper Source Type: research

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