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Percutaneous Left Atrial Appendage Closure in a Patient with Diffuse Alveolar Hemorrhaging Associated with Anticoagulant Therapy and Atrial Fibrillation: A Case Report
Intern Med. 2021 Nov 27. doi: 10.2169/internalmedicine.8551-21. Online ahead of print.ABSTRACTDiffuse alveolar hemorrhaging (DAH) due to oral anticoagulation (OAC) is a life-threatening condition that leads to severe respiratory failure. There is a clinical dilemma in that OAC-induced DAH often forces the discontinuation of OAC therapy and the administration of high-dose corticosteroids, which increases the risk of stroke and cardiovascular events. We herein report the first case of OAC-induced DAH and atrial fibrillation (AF) in a patient who completely discontinued OAC therapy and high-dose corticosteroids after experien...
Source: Internal Medicine - November 29, 2021 Category: Internal Medicine Authors: Takaaki Ogoshi Masato Fukunaga Yu Suzuki Yusuke Taura Kazuhiro Yatera Source Type: research

Cerebral Venous Thromboembolism in Antiphospholipid Syndrome Successfully Treated with the Combined Use of an Anti-Xa Inhibitor and Corticosteroid.
Authors: Sugie M, Iizuka N, Shimizu Y, Ichikawa H Abstract We herein report a case presenting with cerebral venous sinus thrombosis (CVST) associated with primary antiphospholipid syndrome (APS). The patient developed recurrent CVST followed by a hemorrhagic ischemic stroke despite the use of warfarin during the appropriate therapeutic window. Thus, we substituted warfarin to rivaroxaban with prednisolone and obtained a good clinical course. In addition to the effect of prednisolone of inhibiting elevated lupus anticoagulants and the recurrence of arterial thrombosis, rivaroxaban may prevent CVST and inhibit hyperc...
Source: Internal Medicine - December 6, 2015 Category: Internal Medicine Tags: Intern Med Source Type: research