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An assessment of point‐of‐care measurement of INR using the Coaguchek®XS Plus system in the setting of acute ischaemic stroke
ConclusionPoint of care INR testing correlates well with laboratory values. The results in this study mostly relate to levels in the normal range. We suggest that it can be appropriately used to shorten door‐to‐needle time.
Source: Internal Medicine Journal - July 30, 2013 Category: Internal Medicine Authors: Dawn Nusa, Isabel Harvey, Abdulrahman Y Almansouri, Simogne Wright, Terry Neeman, Omar Ahmad, Andrew R. Hughes, Christian J. Lueck Tags: Original Article Source Type: research

Stroke thrombolysis in patients taking dabigatran
Abstract Stroke thrombolysis is becoming a common practice in Australian and New Zealand hospitals. There are no established guidelines for thrombolysis of patients who are taking dabigatran, and accurate medication reconciliation may not be possible. Patients with normal activated partial thromboplastin time are unlikely to have clinically significant dabigatran concentration in the blood. For safest outcomes, we suggest incorporating thrombin time assay for acute stroke patients suspected to be taking dabigatran.
Source: Internal Medicine Journal - July 11, 2013 Category: Internal Medicine Authors: S. Jayathissa, J. Gommans, P. Harper Tags: Brief Communication Source Type: research

Minimizing Time to Treatment: Targeted Strategies to Minimize Time to Thrombolysis for Acute Ischaemic Stroke
ConclusionTime to thrombolysis delays are multi‐factorial. Effective reduction of time delays for acute ischaemic stroke requires the correct identification of and targeted strategies to overcome time barriers.
Source: Internal Medicine Journal - June 5, 2013 Category: Internal Medicine Authors: Yi Jing Tai, Bernard Yan Tags: Original Article Source Type: research

Recent advances in the management of transient ischaemic attack: a clinical review
Abstract Transient ischaemic attack (TIA) if untreated carries a high risk of early stroke and is associated with poorer long‐term survival. There have been recent advances in the understanding of TIA, its investigations, management and organisation of services for patient care. Clinically, patients are diagnosed TIA if they have transient sudden‐onset focal neurological symptoms which usually completely and rapidly resolve by presentation. Patients with residual symptoms should be evaluated as potentially having stroke, if they present within 4.5 h of onset, should be urgently evaluated for their potential eligibili...
Source: Internal Medicine Journal - April 1, 2013 Category: Internal Medicine Authors: T. G. Phan, L. Sanders, V. Srikanth Tags: Review Source Type: research

Novel use of modafinal to treat severe physical and cognitive impairment post‐stroke
Source: Internal Medicine Journal - February 27, 2013 Category: Internal Medicine Authors: S. Geffen, K. Shum, H. M. Tan Tags: Letter to the Editor Source Type: research

Does measurement of ankle‐brachial index contribute to prediction of adverse health outcomes in older Chinese people?
ConclusionsABI measurement (<0.9) predicted adverse outcomes with high specificity but low sensitivity. However it added little incremental value to prediction of adverse outcomes using traditional cardiovascular risk factors.
Source: Internal Medicine Journal - February 21, 2013 Category: Internal Medicine Authors: J Woo, J Leung Tags: Original Article Source Type: research

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