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Perioperative management of new oral anticoagulants in patients undergoing elective surgery at a tertiary hospital
ConclusionConsiderable discordance exists between guideline recommendations and perioperative NOAC management. Assistive tools are required that better align decision making with current best practice.
Source: Internal Medicine Journal - June 7, 2017 Category: Internal Medicine Authors: Henry Wamala, Ian A Scott, Xenia Caney Tags: Original Article Source Type: research

Burden of Atrial Fibrillation: A Retrospective Review of Patients Presenting to Acute Medical Services
ConclusionAnti‐coagulation for stroke prevention in AF remains under‐utilised in eligible patients presenting to acute medical services at a tertiary level hospital.
Source: Internal Medicine Journal - June 30, 2016 Category: Internal Medicine Authors: Evan Jolliffe, Vivian Fu, Jeremiah Lanford, Mark Weatherall, Ian Rosemergy Tags: Original Article Source Type: research

Heparin‐based treatment to prevent symptomatic deep venous thrombosis, pulmonary embolism or death in general medical inpatients is not supported by best evidence
This study aims to determine whether current clinical guidelines for HVTEp are appropriate for medical patients. We searched medical databases for original randomised placebo‐controlled studies of HVTEp in medical patients, excluding those with stroke and in intensive care. From 401 potentially relevant studies, we selected eight, which included over 16 000 patients. HVTEp decreased the incidence of all deep venous thromboses (DVT): 4.3% in the placebo group versus 2.3% in the treatment group, P = 0.002, number needed to treat, 50. However, this treatment effect was not seen for symptomatic DVT: 1.2% versus 0.9%, P = 0...
Source: Internal Medicine Journal - November 4, 2014 Category: Internal Medicine Authors: A. Spencer, T. Cawood, C. Frampton, D. Jardine Tags: Current Controversies Source Type: research

Elevated mean platelet volume is associated with silent cerebral infarction
ConclusionMPV is a novel index for SCI regardless of classical cardiovascular risk factors.
Source: Internal Medicine Journal - April 21, 2014 Category: Internal Medicine Authors: Bing Li, Xin Liu, Zhi‐gang Cao, Ying Li, Tie‐min Liu, Rui‐tao Wang Tags: Original Article Source Type: research