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Overlapping Mechanisms of Exertional Heat Stroke and Malignant Hyperthermia: Evidence vs. Conjecture
AbstractExertional heat stroke (EHS) and malignant hyperthermia (MH) are life-threatening conditions, triggered by different environmental stimuli that share several clinical symptoms and pathophysiological features. EHS manifests during physical activity normally, but not always, in hot and humid environments. MH manifests during exposure to haloalkane anesthetics or succinylcholine, which leads to a rapid, unregulated release of calcium (Ca2+) within the skeletal muscles inducing a positive-feedback loop within the excitation –contraction coupling mechanism that culminates in heat stroke-like symptoms, if not rapidly r...
Source: Sports Medicine - July 5, 2020 Category: Sports Medicine Source Type: research

Does Replacing Sodium Excreted in Sweat Attenuate the Health Benefits of Physical Activity?
Abstract International guidelines suggest limiting sodium intake to 86-100 mmol/day, but average intake exceeds 150 mmol/day. Participants in physical activities are, however, advised to increase sodium intake before, during and after exercise to ensure euhydration, replace sodium lost in sweat, speed rehydration and maintain performance. A similar range of health benefits is attributable to exercise and to reduction in sodium intake, including reductions in blood pressure (BP) and the increase of BP with age, reduced risk of stroke and other cardiovascular diseases, and reduced risk of osteoporosis and dementia. ...
Source: International Journal of Sport Nutrition and Exercise Metabolism - February 3, 2016 Category: Sports Medicine Authors: Turner MJ, Avolio AP Tags: Int J Sport Nutr Exerc Metab Source Type: research