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Urgent Carotid Surgery and Stenting May Be Safe After Systemic Thrombolysis for Stroke Clinical Sciences
Conclusions— Urgent carotid endarterectomy or carotid artery stenting after thrombolysis for stroke may be safe without increased risk of serious complications.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Koraen-Smith, L., Troeng, T., Bjorck, M., Kragsterman, B., Wahlgren, C.-M., on behalf of the Swedish Vascular Registry and the Riks-Stroke Collaboration, This work was supported by the Steering Committee of the Swedish Vascular Registry (Swedvasc):, Krags Tags: Acute Cerebral Infarction, Carotid Stenosis, Emergency treatment of Stroke, Carotid endarterectomy, Angioplasty and Stenting Clinical Sciences Source Type: research

Determinants and Outcomes of Stroke Following Percutaneous Coronary Intervention by Indication Clinical Sciences
Conclusions— Hemorrhagic and ischemic stroke complications are uncommon, but serious complications can occur after PCI and are independently associated with worse mortality and major adverse cardiovascular events outcomes in both the elective and acute coronary syndrome setting irrespective of stroke type. Our study provides a better understanding of the risk factors and prognosis of stroke after PCI by procedure type, allowing physicians to provide more informed advice around stroke risk after PCI and counsel patients and their families around outcomes if such neurological complications occur.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Myint, P. K., Kwok, C. S., Roffe, C., Kontopantelis, E., Zaman, A., Berry, C., Ludman, P. F., de Belder, M. A., Mamas, M. A., on behalf of the British Cardiovascular Intervention Society and the National Institute for Cardiovascular Outcomes Research Tags: Percutaneous Coronary Intervention, Intracranial Hemorrhage, Ischemic Stroke Clinical Sciences Source Type: research

Acute Reperfusion Therapy and Stroke Care in Asia After Successful Endovascular Trials Understanding and Applying the Endovascular Trials
The current status of and prospects for acute stroke care in Asia in the situation where both intravenous thrombolysis and endovascular therapies have been recognized as established strategies for acute stroke are reviewed. Of 15 million people annually having stroke worldwide, 9 million are Asians. The burdens of both ischemic and hemorrhagic strokes are severe in Asia. The unique features of stroke in Asia include susceptibility to intracranial atherosclerosis, high prevalence of intracerebral hemorrhage, effects of dietary and lifestyle habits, and several disorders with genetic causes. These features affect acute strok...
Source: Stroke - May 22, 2015 Category: Neurology Authors: Toyoda, K., Koga, M., Hayakawa, M., Yamagami, H. Tags: Emergency treatment of Stroke, Anticoagulants, Thrombolysis, Angioplasty and Stenting Understanding and Applying the Endovascular Trials Source Type: research

Endovascular Thrombectomy for Anterior Circulation Stroke: Systematic Review and Meta-Analysis Clinical Sciences
Conclusions— ET improves good outcomes after anterior circulation stroke. ET should be strongly considered for all patients presenting within 6 hours of onset with a stroke affecting a proximal, anterior circulation vessel without a contraindication to ET.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Yarbrough, C. K., Ong, C. J., Beyer, A. B., Lipsey, K., Derdeyn, C. P. Tags: Other Stroke Treatment - Medical, Angioplasty and Stenting Clinical Sciences Source Type: research

Nonprocedural Symptomatic Infarction and In-Stent Restenosis After Intracranial Angioplasty and Stenting in the SAMMPRIS Trial (Stenting and Aggressive Medical Management for the Prevention of Recurrent Stroke in Intracranial Stenosis) Clinical Sciences
Conclusions—Symptomatic ISR occurred in at least 1 of 7 patients in SAMMPRIS by 3 years of follow-up and was likely responsible for the majority of nonprocedural cerebral infarctions.Clinical Trial Registration—URL: https://clinicaltrials.gov. Unique identifier: NCT00576693.
Source: Stroke - May 22, 2017 Category: Neurology Authors: Colin P. Derdeyn, David Fiorella, Michael J. Lynn, Tanya N. Turan, George A. Cotsonis, Bethany F. Lane, Jean Montgomery, L. Scott Janis, Marc I. Chimowitz Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Restenosis, Stenosis Original Contributions Source Type: research

Computed Tomographic Angiography and Cerebral Blood Volume Can Predict Final Infarct Volume and Outcome After Recanalization Clinical Sciences
Conclusions— CTASI and CBV were better at predicting 24-hour infarct and outcome than NECT. Appropriate advanced imaged guided selection may improve outcomes in large-vessel stroke treated with the newest techniques.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Lum, C., Ahmed, M. E., Patro, S., Thornhill, R., Hogan, M., Iancu, D., Lesiuk, H., dos Santos, M., Dowlatshahi, D., on behalf of the Ottawa Stroke Research Group (OSRG) Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging, Angioplasty and Stenting Clinical Sciences Source Type: research

Subarachnoid Hemorrhage in a Multimodal Approach Heavily Weighted Toward Mechanical Thrombectomy With Solitaire Stent in Acute Stroke Original Contributions
Conclusions— SAH on post-therapeutic computerized tomography scans were not uncommon after primary mechanical thrombectomy with a Solitaire stent, but they seemed to be benign. Rescue angioplasty and unidentified, small vessel ruptures due to mechanical stretch during stent retrieval might give rise to these lesions.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Yoon, W., Jung, M. Y., Jung, S. H., Park, M. S., Kim, J. T., Kang, H. K. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging, Intracerebral Hemorrhage Original Contributions Source Type: research

Endovascular Clot Retrieval Therapy: Implications for the Organization of Stroke Systems of Care in North America Understanding and Applying the Endovascular Trials
Endovascular acute ischemic stroke therapy is now proven by randomized controlled trials to produce large, clinically meaningful benefits. In response, stroke systems of care must change to increase timely and equitable access to this therapy. In this review, we provide a North American perspective on implications for stroke systems, focusing on the United States and Canada, accompanied by initial recommendations for changes. Most urgently, every community must create access to a hospital that can safely and quickly provide intravenous tissue-type plasminogen activator and immediately transfer appropriate patients onward t...
Source: Stroke - May 22, 2015 Category: Neurology Authors: Smith, E. E., Schwamm, L. H. Tags: Health policy and outcome research, Acute Cerebral Infarction, Acute Stroke Syndromes, Angioplasty and Stenting Understanding and Applying the Endovascular Trials Source Type: research

Late Stroke: Comparison of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With Multivessel Disease and Unprotected Left Main Disease: A Meta-Analysis and Review of Literature Clinical Sciences
Conclusions— There is a significantly lower risk of stroke within 30 days and cumulative stroke with PCI as compared with CABG up to year 5. There is no late catch up of stroke in the PCI arm. The risk of stroke should be weighed in deciding between revascularization strategies.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Athappan, G., Chacko, P., Patvardhan, E., Gajulapalli, R. D., Tuzcu, E. M., Kapadia, S. R. Tags: CV surgery: coronary artery disease Clinical Sciences Source Type: research

Incidence, Trends, and Predictors of Ischemic Stroke 30 Days After an Acute Myocardial Infarction Clinical Sciences
Conclusions— The incidence of ischemic stroke within 30 days of an AMI has decreased during the period 1998 to 2008. This decrease is associated with increased use of acetylsalicylic acid, P2Y12 inhibitors, statins, and percutaneous coronary intervention.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Kajermo, U., Ulvenstam, A., Modica, A., Jernberg, T., Mooe, T. Tags: Risk Factors, Acute myocardial infarction, Acute Cerebral Infarction, Epidemiology Clinical Sciences Source Type: research

Incidence, Trends, and Predictors of Ischemic Stroke 1 Year After an Acute Myocardial Infarction Clinical Sciences
Conclusions— The risk of ischemic stroke within a year after myocardial infarction is substantial but has clearly been reduced during the studied time period. The major predictive factors found to correlate well with previous investigations. Reperfusion treatment, thrombocyte aggregation inhibition, and lipid lowering are the main contributors to the observed risk reduction.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Ulvenstam, A., Kajermo, U., Modica, A., Jernberg, T., Soderstrom, L., Mooe, T. Tags: Platelet function inhibitors, Acute myocardial infarction, Acute Cerebral Infarction, Platelets Clinical Sciences Source Type: research

Length of carotid stenosis predicts peri‐procedural stroke or death and restenosis in patients randomized to endovascular treatment or endarterectomy
ConclusionsIncreasing stenosis length is an independent risk factor for peri‐procedural stroke or death in endovascular treatment and carotid endarterectomy, without favoring one treatment over the other. However, the excess restenosis rate after endovascular treatment compared with carotid endarterectomy increases with longer stenosis at baseline. Stenosis length merits further investigation in carotid revascularisation trials.
Source: International Journal of Stroke - August 1, 2013 Category: Neurology Authors: Leo H. Bonati, Jörg Ederle, Joanna Dobson, Stefan Engelter, Roland L. Featherstone, Peter A. Gaines, Jonathan D. Beard, Graham S. Venables, Hugh S. Markus, Andrew Clifton, Peter Sandercock, Martin M. Brown, Tags: Research Source Type: research

Optimizing Prediction Scores for Poor Outcome After Intra-Arterial Therapy in Anterior Circulation Acute Ischemic Stroke Clinical Sciences
Conclusions— The HIAT2 score, which combines clinical and imaging variables, performed better than all previous scores in predicting poor outcome after IAT for anterior circulation large artery occlusions.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Sarraj, A., Albright, K., Barreto, A. D., Boehme, A. K., Sitton, C. W., Choi, J., Lutzker, S. L., Sun, C.-H. J., Bibars, W., Nguyen, C. B., Mir, O., Vahidy, F., Wu, T.-C., Lopez, G. A., Gonzales, N. R., Edgell, R., Martin-Schild, S., Hallevi, H., Chen, P. Tags: Acute Cerebral Infarction, Angioplasty and Stenting Clinical Sciences Source Type: research

Alberta Stroke Program Early Computed Tomography Score to Select Patients for Endovascular Treatment: Interventional Management of Stroke (IMS)-III Trial Clinical Sciences
Conclusions— ASPECTS is a strong predictor of outcome and a predictor of reperfusion. ASPECTS did not identify a subpopulation of subjects that particularly benefitted from endovascular therapy immediately after routine intravenous tPA. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00359424.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Hill, M. D., Demchuk, A. M., Goyal, M., Jovin, T. G., Foster, L. D., Tomsick, T. A., von Kummer, R., Yeatts, S. D., Palesch, Y. Y., Broderick, J. P., for the IMS3 Investigators Tags: Angiography, Computerized tomography and Magnetic Resonance Imaging, Thrombolysis, Angioplasty and Stenting Clinical Sciences Source Type: research

Pathogenesis and Risk Factors for Cerebral Infarct After Surgical Aortic Valve Replacement Brief Reports
Conclusions— The principal mechanism of acute cerebral infarction after aortic valve replacement is embolism. There are distinct factors associated with watershed and embolic infarct, some of which may be modifiable.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Massaro, A., Messe, S. R., Acker, M. A., Kasner, S. E., Torres, J., Fanning, M., Giovannetti, T., Ratcliffe, S. J., Bilello, M., Szeto, W. Y., Bavaria, J. E., Mohler, E. R., Floyd, T. F., for the Determining Neurologic Outcomes From Valve Operations (DeNO Tags: Valvular Heart Disease, Magnetic Resonance Imaging (MRI), Cardiovascular Surgery, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

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