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Specialty: Neurology
Source: Neurology Clinical Practice

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Total 200 results found since Jan 2013.

Diffusion-Restricted Lesions of the Splenium: Clinical Presentation, Radiographic Patterns, and Patient Outcomes
Discussion Vascular DR lesions of the splenium were more common than CLOCCs and other etiologies in this cohort. While splenial DR lesions can present a clinical challenge, their associated clinical and radiographic characteristics may predict outcome and guide prognosis.
Source: Neurology Clinical Practice - September 8, 2023 Category: Neurology Authors: Stamm, B., Lineback, C. M., Tang, M., Jia, D. T., Chrenka, E., Sorond, F., Sabayan, B. Tags: MRI, DWI, All Cerebrovascular disease/Stroke Research Article Source Type: research

Death and ADL Dependency After Scoring Zero on the NIHSS: A Swedish Retrospective Registry-Based Study
Discussion One of 17 patients has either died or become ADL-dependent 3 months after a 0-NIHSS stroke, stressing that these strokes are not always benign. Older and physically inactive patients are at greater risk of an adverse outcome.
Source: Neurology Clinical Practice - September 1, 2023 Category: Neurology Authors: Darehed, D., Reinholdsson, M., Viktorisson, A., Abzhandadze, T., Sunnerhagen, K. S. Tags: Outcome research, All Cerebrovascular disease/Stroke, Cohort studies Research Article Source Type: research

Observational Study of Patients Hospitalized With Neurologic Events After SARS-CoV-2 Vaccination, December 2020-June 2021
Discussion All cases in this study were determined to have at least 1 risk factor and/or known etiology accounting for their neurologic syndromes. Our comprehensive clinical review of these cases supports the safety of mRNA COVID-19 vaccines.
Source: Neurology Clinical Practice - May 25, 2023 Category: Neurology Authors: Kim, C. Y., McNeill, E. N., Young, C., King, F., Clague, M., Caldwell, M., Boruah, A., Zucker, J., Thakur, K. T. Tags: Autoimmune diseases, Post-infectious, Inclusion, Diversity, Equity, Anti-racism, and Social Justice (IDEAS), COVID-19 Research Article Source Type: research

Neurobrucellosis Mimicking Primary CNS Vasculitis--Should We Perform CSF Metagenomics Before Brain Biopsy?: A Case Report
Discussion Brucellosis is an endemic disease in developing countries and may mimic PCNSV. Our patient fulfilled the criteria for possible PCNSV; however, brain biopsy was inconsistent with PCNSV, and CSF mNGS disclosed neurobrucellosis. This case illustrates the importance of CSF mNGS in the differential diagnosis of CNS vasculitis.
Source: Neurology Clinical Practice - May 9, 2023 Category: Neurology Authors: Mathias, M. B., Menezes, F. G., Fernandes, G. B. P., Paes, V. R., Silva, G. S., Braga-Neto, P., Barbosa, A. A., De Oliveira, A. C. P., Baccin, C. E., Dutra, L. A. Tags: Vasculitis Clinical/Scientific Note Source Type: research

Stroke in Patients With Common Noncancerous Gynecologic Diseases: A Multicenter Study in Japan
Discussion In patients with common noncancerous gynecologic diseases, hypercoagulopathy may play a role in the pathogenesis of ischemic stroke/TIA without CSMs.
Source: Neurology Clinical Practice - April 27, 2023 Category: Neurology Authors: Yamashiro, K., Sato, T., Nito, C., Ueno, Y., Kawano, H., Chiba, T., Nishihira, T., Mizuno, T., Ishizuka, K., Iguchi, Y., Kimura, K., Kitagawa, K., Koga, M., Hirano, T., Kameda, T., Takekawa, H., Urabe, T., Taneichi, A., Fujiwara, H., Fujimoto, S., Hattori Tags: All Cerebrovascular disease/Stroke Research Article Source Type: research

Clinical Biomarkers and Prediction Models for Poststroke Epilepsy: Have We Settled the Scores Yet?
In an era of time-dependent reperfusion and recanalization therapy for stroke leading to improved survival, there is a growing population at risk of poststroke epilepsy (PSE). Accumulating evidence suggests a multidirectional interaction among stroke, PSE, and dementia in stroke survivors. There is no evidence to justify prophylactic antiseizure medication (ASM) to reduce these morbidities. Although several predictive molecular biomarkers and scoring models have been proposed, they remain inadequately validated for stratifying risk and indicating who will benefit from prophylactic ASM. Studies leveraging advances in geneti...
Source: Neurology Clinical Practice - March 14, 2023 Category: Neurology Authors: Yonas, A. S., Meschia, J. F., Feyissa, A. M. Tags: Stroke in young adults, All Cerebrovascular disease/Stroke, EEG; see Epilepsy/Seizures, Screening in epidemiology, All Epilepsy/Seizures Commentary Source Type: research

Inequities in Telemedicine Use Among Patients With Stroke and Cerebrovascular Diseases: A Tricenter Cross-sectional Study
Discussion In our diverse cohort across 3 centers, we found differences in TM visit type by race and insurance early during the COVID-19 pandemic. These findings suggest disparities in VTM access across different stroke populations. As VTM remains an integral part of outpatient neurology practice, steps to ensure equitable access are essential.
Source: Neurology Clinical Practice - March 14, 2023 Category: Neurology Authors: Naqvi, I. A., Cohen, A. S., Kim, Y., Harris, J., Denny, M. C., Strobino, K., Bicher, N., Leite, R. A., Sadowsky, D., Adegboye, C., Okpala, N., Okpala, M., Savitz, S. I., Marshall, R. S., Sharrief, A. Tags: All Health Services Research, All Cerebrovascular disease/Stroke, Underserved populations, Health disparities Research Article Source Type: research

Rescue Epidural Saline Patch for Comatose Patients With Refractory Convexity Spontaneous Subacute Subdural Hematoma: Case Report
In this study, we report 4 cases of refractory CSSSH treated with rescue epidural saline patch, although history and imaging studies showed no evidence of SIH. Methods All 4 patients received a lumbar saline epidural rescue patch for consciousness impairment associated with refractory CSSSH, and one is particularly detailed. No patient had typical radiologic signs of SIH or, on the contrary, uncal herniation that could have indicated intracranial hypertension. Results The Glasgow Coma Scale score improved significantly in the days after application of the epidural patch in 3 patients. All patients showed an improvement o...
Source: Neurology Clinical Practice - March 10, 2023 Category: Neurology Authors: Roy, M., Welschbillig, S., Cantier, M., Chauvet, D., Bourdillon, P., Engrand, N. Tags: Low pressure syndrome, Other cerebrovascular disease/ Stroke, Coma, Critical care Clinical/Scientific Note Source Type: research

Intracranial Hemorrhage as a Marker for Mycotic Aneurysm in Patients With Infective Endocarditis
Discussion Patients with left-sided and right-sided endocarditis with PFO and ICH on CNS imaging were more likely to have mycotic aneurysms detected through DSA than similar patients without ICH. Routine DSA screening for mycotic aneurysms may not be required in patients with endocarditis undergoing evaluation for valve surgery who present without ICH on CNS imaging.
Source: Neurology Clinical Practice - March 10, 2023 Category: Neurology Authors: Williams, T. J., Starr, M., El-Dalati, S. Tags: CT, MRI, Bacterial infections, Embolism, Intracerebral hemorrhage Research Article Source Type: research

Best Practice Recommendations for Stroke Vascular Imaging During Iodinated Contrast Shortage
GE Healthcare© announced on April 19, 2022, that their main factory and distributor of iodinated contrast had experienced a temporary shutdown because of COVID-19 outbreak in Shanghai, China. This, along with other supply chain issues, led to a worldwide shortage of iodinated contrast agents, Omnipaque and Visipaque. Our Comprehensive Stroke Center was confronted with the cascading effect of this iodinated contrast material shortage. We took immediate steps to revise our protocols and processes to continue to provide high-quality care to our stroke patients. A multidisciplinary working group comprised of representativ...
Source: Neurology Clinical Practice - March 3, 2023 Category: Neurology Authors: Bhole, R., Solenski, N. J., Donahue, J. H., Kellogg, R. T., Roach, N. N., Chapman, S. N., Worrall, B. B., Evans, A. J., Patel, S. H., Mukherjee, S., Park, M. S., Southerland, A. M. Tags: Decision analysis, Medical care, All Cerebrovascular disease/Stroke, All Practice Management Commentary Source Type: research

Early Discontinuation of Phenobarbital After Acute Symptomatic Neonatal Seizures in the Term Newborn
In this study, we present a unified framework for phenobarbital discontinuation after resolution of acute symptomatic seizures in the setting of brain injury of the newborn.
Source: Neurology Clinical Practice - February 16, 2023 Category: Neurology Authors: Carrasco, M., Bonifacio, S. L., deVeber, G., Chau, V., on behalf of the Newborn Brain Society Guidelines, and Publications Committee Tags: EEG, Neonatal seizures Commentary Source Type: research

Carotid Intimal Sarcoma Presenting as Large Vessel Occlusion and Diagnosed by Embolus Histopathology: Case Report
We report the case of a patient who presented with acute embolic ischemic stroke and was found to have IS based on a histopathologic evaluation of his embolectomy specimen. Subsequent comprehensive imaging studies failed to detect a primary tumor site. Multidisciplinary interventions including a course of radiotherapy were performed. The patient died of recurrent multifocal strokes 92 days after diagnosis. Discussion Meticulous histopathologic analysis should be conducted on cerebral embolectomy specimens. Histopathology may be useful in diagnosing IS.
Source: Neurology Clinical Practice - January 19, 2023 Category: Neurology Authors: Johnson, M. D., Rogers, E. J., Khan, M. W., McMullen, P. D., Akkipeddi, S. M. K., Mattingly, T., Benesch, C. G., Bender, M. T. Tags: Clinical/Scientific Note Source Type: research

Exploring Stroke Risk Factors and Outcomes in Sexual and Gender Minority People
Discussion SGM people may have different risk factors, different mechanisms of stroke, and higher risk of recurrent stroke compared with non-SGM people. Standardized collection of sexual orientation and gender identity would enable larger studies to further understand disparities, leading to secondary prevention strategies.
Source: Neurology Clinical Practice - January 18, 2023 Category: Neurology Authors: Diaz, M. A., Rosendale, N. Tags: Research Article Source Type: research

Enrollment of Participants From Marginalized Racial and Ethnic Groups: A Comparative Assessment of the STEADY-PD III and SURE-PD3 Trials
This study used data from The Safety, Tolerability, and Efficacy Assessment of Isradipine for Parkinson Disease (STEADY-PD III; NCT02168842) and the Study of Urate Elevation in Parkinson’s Disease (SURE-PD3; NCT02642393).
Source: Neurology Clinical Practice - January 18, 2023 Category: Neurology Authors: Di Luca, D. G., Macklin, E. A., Hodgeman, K., Lopez, G., Pothier, L., Callahan, K. F., Lowell, J., Chan, J., Videnovic, A., Lungu, C., Lang, A. E., Litvan, I., Schwarzschild, M. A., Simuni, T. Tags: Parkinson's disease/Parkinsonism, Clinical trials Methodology/study design, Inclusion, Diversity, Equity, Anti-racism, and Social Justice (IDEAS), Health disparities, Structural and social determinants of health RESEARCH ARTICLE Source Type: research

Pediatric Moyamoya Syndrome Secondary to Tuberculous Meningitis: A Case Report
We report the case of a female patient who initially presented at 6 years of age with TBM and developed moyamoya syndrome requiring revascularization surgery. Results She was found to have basilar meningeal enhancement and right basal ganglia infarcts. She was treated with 12 months of antituberculosis therapy and 12 months of enoxaparin and maintained on daily aspirin indefinitely. However, she developed recurrent headaches and transient ischemic attacks and was found to have progressive bilateral moyamoya arteriopathy. At age 11 years, she underwent bilateral pial synangiosis for the treatment of her moyamoya syndrome. ...
Source: Neurology Clinical Practice - January 18, 2023 Category: Neurology Authors: Kappel, A. D., Lehman, L. L., Northam, W. T., See, A. P., Smith, E. R. Tags: Clinical/Scientific Note Source Type: research