• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Fetal Alcohol Exposure Alters Blood Flow and Neurological Responses to Transient Cerebral Ischemia in Adult Mice.
CONCLUSIONS: Our data collectively show that PAE adult mice exhibit a persistent, long-term loss of cranially directed blood flow, and decreased capacity to compensate for brain trauma due to acute-onset adult diseases like ischemic stroke. PMID: 27987329 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - December 16, 2016 Category: Addiction Authors: Bake S, Gardner R, Tingling JD, Miranda RC, Sohrabji F Tags: Alcohol Clin Exp Res Source Type: research

Fetal Alcohol Exposure Alters Blood Flow and Neurological Responses to Transient Cerebral Ischemia in Adult Mice
ConclusionsOur data collectively show that PAE adult mice exhibit a persistent, long‐term loss of cranially directed blood flow, and decreased capacity to compensate for brain trauma due to acute‐onset adult diseases like ischemic stroke. Our study assessed long‐term consequences of prenatal alcohol exposure (PAE) on blood flow and on behavioral outcomes following unilateral middle cerebral artery occlusion (MCAo)‐induced transient ischemic stroke in adults. PAE resulted in a significant age‐related decrease in blood acceleration in mature adult and middle‐aged mice, specifically in the carotid artery. Followi...
Source: Alcoholism: Clinical and Experimental Research - December 16, 2016 Category: Addiction Authors: Shameena Bake, Rachel Gardner, Joseph D. Tingling, Rajesh C. Miranda, Farida Sohrabji Tags: Original Article Source Type: research