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Edaravone dexborneol alleviates cerebral ischemia-reperfusion injury through NF- κB/NLRP3 signal pathway
In conclusion, this study indicates that C.EDA alleviates I/R injury by blocking the activation of the NLRP3 inflammasome and regulating the polarization of M1/M2 microglia via the NF-κB signal pathway.PMID:37475155 | DOI:10.1002/ar.25296
Source: Anatomical Record - July 21, 2023 Category: Anatomy Authors: Guanghong Shen Chengjian Lou Qunfeng Li Bingxin Zhao Yuhuan Luo Fei Wu Dian Jiao Marong Fang Yu Geng Source Type: research

Comparative efficacy and safety of acupuncture and Western medicine for poststroke thalamic pain
Anat Rec (Hoboken). 2022 Mar 3. doi: 10.1002/ar.24902. Online ahead of print.ABSTRACTPoststroke thalamic pain (PSTP) is one of the most common sequelae following stroke. Analgesics, antidepressants, anticonvulsants, and surgical treatment are conventional treatment methods of PSTP, but these methods have limited efficacy, cost more, and cause a likelihood of adverse reactions. Clinical studies have shown that acupuncture has a significant analgesic effect on PSTP without obvious side effects. But, there is a lack of high-quality evidence concerning its effectiveness and safety to support its use. Therefore, this study aime...
Source: Anatomical Record - March 3, 2022 Category: Anatomy Authors: Jiju Yang Xinyi Li Chong Li Ke He Yang Wu Haiming Lin Xianfei Xie Fan Zhang Huifeng Hao Guihua Tian Source Type: research

Scalp acupuncture enhances local brain regions functional activities and functional connections between cerebral hemispheres in acute ischemic stroke patients
This study aimed to explore the changes in functional connections between cerebral hemispheres and local brain regions functional activities in patients with acute ischemic stroke (AIS) treated with International Standard Scalp Acupuncture (ISSA). Thirty patients with middle cerebral artery AIS in the dominant hemisphere were selected and randomly divided into two groups such as the control group and the scalp acupuncture group, with 15 patients in each group. Patients in the control group were treated with conventional Western medicine, while patients in the scalp acupuncture group received ISSA (acupuncture at the pariet...
Source: Anatomical Record - August 25, 2021 Category: Anatomy Authors: Huacong Liu Yijing Jiang Ningning Wang Han Yan Lanpin Chen Jingchun Gao Jiping Zhang Shanshan Qu Songyan Liu Gang Liu Yong Huang Junqi Chen Source Type: research

The "dog paddle": Stereotypic swimming gait pattern in different dog breeds.
Abstract The term "dog paddle" has been applied to the swimming behavior of various terrestrial and aquatic species. Dog paddling refers to a form of drag-based, paddle propulsion in which the limbs are oriented underneath the body and moved through an arc. Despite the ubiquity of the term, there has been no analysis of the swimming kinematics of dogs. Underwater video was recorded of surface swimming dogs (velocity: 0.4-1.1 m/s) for eight individuals from six breeds, ranging in size from Yorkshire Terrier (3.6 kg) to Newfoundland dog (63.5 kg). The quadrupedal paddling stroke was analyzed to determine kinematics ...
Source: Anatomical Record - April 2, 2020 Category: Anatomy Authors: Fish FE, DiNenno NK, Trail J Tags: Anat Rec (Hoboken) Source Type: research

Progesterone effects in the nervous system.
This article is protected by copyright. All rights reserved. PMID: 30951258 [PubMed - as supplied by publisher]
Source: Anatomical Record - April 4, 2019 Category: Anatomy Authors: Theis V, Theiss C Tags: Anat Rec (Hoboken) Source Type: research

Peripheral arteries may be reliable indicators of coronary vascular disease.
This article is protected by copyright. All rights reserved. PMID: 28244238 [PubMed - as supplied by publisher]
Source: Anatomical Record - February 27, 2017 Category: Anatomy Authors: Hoehmann CL, Futterman B, Beatty BL Tags: Anat Rec (Hoboken) Source Type: research

Anti-inflammatory and neuroprotective effects of Triptolide via the NF-κB signaling pathway in a rat MCAO model.
This article is protected by copyright. All rights reserved. PMID: 26575184 [PubMed - as supplied by publisher]
Source: Anatomical Record - November 17, 2015 Category: Anatomy Authors: Bai S, Hu Z, Yang Y, Yin Y, Li W, Wu L, Fang M Tags: Anat Rec (Hoboken) Source Type: research

Evaluation of Hippocampal Injury and Cognitive Function Induced by Embolization in the Rat Brain.
Abstract Embolism is responsible for at least 20% of all stroke and half of cerebral infarctions. A number of animal models have been developed to mimic thromboembolic stroke. However, little aimed directly at hippocampal damage and cognitive function. In the present study, three sizes of emboli (150-178 μm, 74-124 μm, and 48-74 μm) were employed to induce thromboembolic stroke model in rats. Results showed that the diameter of the particle was critical for animal behavioral and histopathological consequences. Hematoxylin-eosin (HE) staining revealed that CA1 and CA2-3, which are two of the main hippocampal sub...
Source: Anatomical Record - June 1, 2013 Category: Anatomy Authors: Zhang HA, Gao M, Chen B, Shi L, Wang Q, Yu X, Xuan Z, Gao L, Du G Tags: Anat Rec (Hoboken) Source Type: research