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Hemophagocytic lymphohistiocytosis diagnosed by bone marrow trephine biopsy in living post-COVID-19 patients: case report and mini-review
AbstractHemophagocytic lymphohistiocytosis (HLH) constitutes a life-threatening inflammatory syndrome. Postmortem histological findings of bone marrow (BM) from COVID-19 patients showed histiocytosis and hemophagocytosis and supported the hypothesis that secondary HLH (sHLH) may be triggered by SARS-CoV-2 infection. However, there are a limited number of sHLH cases in which trephine has been performed in living post-COVID-19 patients. Here we present a recent case and a mini-review of sHLH diagnosed by trephine biopsy in living patients after COVID-19. An 81-year-old man with a past medical history of hypertension, diabete...
Source: Journal of Molecular Histology - June 14, 2022 Category: Laboratory Medicine Source Type: research

Central Nervous System Outcomes of COVID-19
Transl Res. 2021 Sep 30:S1931-5244(21)00244-9. doi: 10.1016/j.trsl.2021.09.002. Online ahead of print.ABSTRACTThe worldwide pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected an estimated 200 million people with over 4 million deaths. Although COVID-19, the disease caused by the SARS-CoV-2 virus, is primarily a respiratory disease, an increasing number of neurologic symptoms have been reported. Some of these symptoms, such as loss of smell or taste, are mild and non-life threatening, while others, such as stroke or seizure, are more critical. Many of these symptoms remain long ...
Source: Translational Research : the journal of laboratory and clinical medicine - October 3, 2021 Category: Laboratory Medicine Authors: Margaret F Doyle Source Type: research

Central nervous system outcomes of COVID-19
Transl Res. 2021 Sep 30:S1931-5244(21)00244-9. doi: 10.1016/j.trsl.2021.09.002. Online ahead of print.ABSTRACTThe worldwide pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected an estimated 200 million people with over 4 million deaths. Although COVID-19, the disease caused by the SARS-CoV-2 virus, is primarily a respiratory disease, an increasing number of neurologic symptoms have been reported. Some of these symptoms, such as loss of smell or taste, are mild and non-life threatening, while others, such as stroke or seizure, are more critical. Many of these symptoms remain long ...
Source: Translational Research : the journal of laboratory and clinical medicine - October 3, 2021 Category: Laboratory Medicine Authors: Margaret F Doyle Source Type: research

Central Nervous System Outcomes of COVID-19
Transl Res. 2021 Sep 30:S1931-5244(21)00244-9. doi: 10.1016/j.trsl.2021.09.002. Online ahead of print.ABSTRACTThe worldwide pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected an estimated 200 million people with over 4 million deaths. Although COVID-19, the disease caused by the SARS-CoV-2 virus, is primarily a respiratory disease, an increasing number of neurologic symptoms have been reported. Some of these symptoms, such as loss of smell or taste, are mild and non-life threatening, while others, such as stroke or seizure, are more critical. Many of these symptoms remain long ...
Source: Translational Research : the journal of laboratory and clinical medicine - October 3, 2021 Category: Laboratory Medicine Authors: Margaret F Doyle Source Type: research

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