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Sudden Sensorineural Hearing Loss Predicts Ischemic Stroke: a Longitudinal Follow-Up Study
Objectives: To investigate the risk of stroke in SSNHL patients. Study Design: A longitudinal follow-up cohort study. Setting: The Korean National Health Insurance Service-National Sample Cohort from 2002 to 2013. Patients: The 4,944 SSNHL participants were matched with 19,776 controls for age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia. The SSNHL subjects were diagnosed (International Classification of Disease [ICD]-10: H91.2), underwent an audiometry examination, and were treated with steroids. The history of hemorrhagic stroke, ischemic stroke, hypertension, diabetes, dyslipide...
Source: Otology and Neurotology - August 16, 2018 Category: ENT & OMF Tags: Sens Orineural Hearing Loss and Tinnitus Source Type: research

Serum Methylarginines and Hearing Loss in a Population-based Cohort of Older Adults
Conclusion: This study showed a significant association between serum concentrations of ADMA and hearing loss for males, consistent with the association between endothelial dysfunction and hearing loss. The opposite effect of L-arginine on hearing loss in males versus females might reflect a different role of this precursor toward nitric oxide versus methylated arginines synthesis. These findings are potentially clinically significant if the association between ADMA and hearing loss is causal, as serum methylarginine levels are modifiable through pharmacotherapeutic/lifestyle interventions.
Source: Otology and Neurotology - March 29, 2018 Category: ENT & OMF Tags: Basic Science Source Type: research

Glomus Tympanicum: A Review of 115 Cases over 4 Decades
Conclusion Surgery remains the treatment of choice for GT, providing a high rate of tumor control and resolution of aural symptoms with a low risk of complications. The surgical approach and extent of resection should be tailored to the patient. Gross total resection can be performed in over 90% of patients; however, leaving a limited adherent tumor remnant on the facial nerve or carotid artery should be considered with advanced infiltrative disease to prevent unnecessary morbidity.
Source: Otolaryngology - Head and Neck Surgery - December 29, 2014 Category: ENT & OMF Authors: Carlson, M. L., Sweeney, A. D., Pelosi, S., Wanna, G. B., Glasscock, M. E., Haynes, D. S. Tags: Otology and Neurotology Source Type: research

Posterior circulation ischemic stroke in childhood and neurofibromatosis type 2
We report the clinical and genetic findings and review the previous literature on vasculopathy reported in association with NF2, with a focus on the symptoms presenting at disease onset. For our case patient, an unpublished germline mutation resulting in frameshift (c.876_877insT) was identified on blood screening. We report our full multidisciplinary assessment with vascular angiography, volumetric MRI and audiometry. Vasculopathy is not currently included in the criteria traditionally used for diagnosis of NF2. We suggest that vascular stroke in childhood may be considered a presenting symptom for NF2.
Source: International Journal of Pediatric Otorhinolaryngology Extra - January 6, 2014 Category: ENT & OMF Authors: Nicolas-Xavier Bonne, Marc Baroncini, Rabih Aboukais, Mark Brandt Lorenz, Franck Broly, Frédérique Dubrulle, Jean-Paul Lejeune, Christophe Vincent Tags: Case reports Source Type: research