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Embolization of Endocardial Vegetation With Stroke Presentation
This case report details the unique cause of death of a 37-year-old Caucasian woman with a history significant for intravenous drug abuse. Before her death, she complained of extremity weakness and pain. Although her death was discovered to be the result of endocarditis, her symptoms were similar to that of a stroke. Autopsy revealed a large endocardial vegetation infecting both the tricuspid and mitral valves and a patent foramen ovale. The subsequent embolization of this vegetation caused blockages in the lungs, liver, and brain. An acute embolization of these vegetations to the bilateral middle cerebral arteries is the ...
Source: The American Journal of Forensic Medicine and Pathology - February 6, 2019 Category: Forensic Medicine Tags: Case Reports Source Type: research

Circulatory microrna in acute myocardial infarction: a candidate biomarker for forensic investigation
MicroRNAs (miRNAs) are small non-coding RNAs regulated a gene expression which associated to many diseases. As they contribute to diverse biological process and respond to various kinds of cellular stress, their utility as diagnostic biomarkers have recently been explored. miRNAs have been detected in various type of human tissues and were used as novel biomarkers in clinical investigation for example; ischemic stroke, acute myocardial infarction (AMI) and several forms of cancer cells. Recently, circulatory miRNA was proved that It could be a potential biomarker to determine a cause of death.
Source: Forensic Science International: Genetics Supplement Series - September 20, 2017 Category: Forensic Medicine Authors: P. Menathung, P. Saengkaeotrakul, K. Rasmeepaisarn, K. Vongpaisarnsin Source Type: research

Circulatory microrna in acute myocardial infarction: A candidate biomarker for forensic investigation
MicroRNAs (miRNAs) are small non-coding RNAs regulated a gene expression which associated to many diseases. As they contribute to diverse biological process and respond to various kinds of cellular stress, their utility as diagnostic biomarkers have recently been explored. miRNAs have been detected in various type of human tissues and were used as novel biomarkers in clinical investigation for example; ischemic stroke, acute myocardial infarction (AMI) and several forms of cancer cells. Recently, circulatory miRNA was proved that It could be a potential biomarker to determine a cause of death.
Source: Forensic Science International: Genetics Supplement Series - September 20, 2017 Category: Forensic Medicine Authors: P. Menathung, P. Saengkaeotrakul, K. Rasmeepaisarn, K. Vongpaisarnsin Source Type: research

Mitral annulus calcification and sudden death
Abstract: Mitral valve annulus calcification is a degenerative cardiac condition often found at autopsy in the elderly. While usually considered incidental to the cause of death, we report two cases where mitral valve annulus calcification with valve stenosis was associated with sudden death. Case 1: a 61-year-old female who had underlying atherosclerosis and hypertension collapsed at home. At autopsy there was marked mitral valve annulus calcification with valve stenosis and cardiomegaly. Case 2: a previously well 74-year-old female collapsed in a toilet. At autopsy there was marked calcification of the mitral valve annul...
Source: Journal of Forensic and Legal Medicine - April 29, 2013 Category: Forensic Medicine Authors: Esther Quick, Roger W. Byard Tags: Case Reviews Source Type: research