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Condition: Stroke
Procedure: Lung Transplant

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Total 372 results found since Jan 2013.

Highly Accurate Continuous Blood Pressure Measurement in LVAD Patients with a Non-Invasive, Non-Oscillometric Wearable Device: A Pilot Study
This study aimed to assess the accuracy of a novel, non-invasive wearable device that provides a continuous measurement of systolic and diastolic BP (Figure 1A).
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: G. Sayer, G.H. Kim, D. Rodgers, B. Chung, A. Nguyen, N. Narang, J. Raikhelkar, S. Kalantari, N. Sarswat, V. Jeevanandam, N. Uriel Source Type: research

Stroke Volume Response to Exercise is Dependent on Disease Severity in Pulmonary Arterial Hypertension
This study aimed to describe changes in stroke volume (SV) during exercise in patients with pulmonary arterial hypertension (PAH) to allow for exercise-based risk stratification.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: C. G öransson, N. Vejlstrup, J. Carlsen Source Type: research

Bayesian Model for Predicting 90 Day Event Free Survival in LVAD Patients
Potential adverse outcomes are often quoted individually to patients (e.g. 4% risk of stroke or bleeding) pre LVAD implantation. However, technical medical aspects may impact their grasp of perceived ‘overall’ risk and hence their ability to match expectations and post-op consequences. We assessed survival free from any major adverse event (MAE) and predict their occurrence within the first 90 days after LVAD implant.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: M. Kanwar, L. Lohmueller, R. Kormos, C. Mcilvennan, S. Bailey, S. Murali, J. Antaki Source Type: research

Flow Performance of the CorWave LVAD Membrane Wave Pump
Implantable long-term blood pumps currently available or in development employ high speed rotary impellers. Use of these devices is currently limited due to relatively high rates of stroke, bleeding complications and infection. A new blood pump technology is under development inspired by the swimming motion of a fish. High frequency, low amplitude linear actuation creates a wave motion on a polymer membrane, gently pushing the blood through the pump. This approach offers a less damaging method for pumping blood, provides full physiologic pulsatility and can operate efficiently over a wide range of operating conditions.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: C.N. Botterbusch, P. Monticone, L. Polverelli Source Type: research

Novel Rat Lung Transplant Model of Primary Graft Dysfunction by Histone Administration
It has been known that intranuclear histones are released into systemic circulation in various medical conditions caused by massive tissue damage, such as stroke or trauma. We hypothesized that a histone-associated lung injury caused in the process of brain deaths of donors is one of risk factors of primary graft dysfunction (PGD) after lung transplantation.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: K. Nakao, M. Anraku, T. Murayama, M. Kawashima, A. Hosoi, J. Nakajima Source Type: research

Prognostic Implications of Intermediate Hemolysis in Continuous Flow Left Ventricular Assist Device Patients
Hemolysis is an early marker of device thrombosis in pts on continuous flow left ventricular assist device (CF-LVAD). For pts with high levels of hemolysis (LDH>700 U/L) treatment with device exchange rather than medical therapy leads to improvement in stroke free survival. We aimed to investigate outcomes and optimal treatment (tx) strategies for outpts on CF-LVAD demonstrating intermediate levels of hemolysis (LDH 500-700 U/L).
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: H. Rosenblum, A. Pinsino, M. Gavalas, A. Zuver, K. Parikh, G. Parkis, M. Flannery, M. Mabasa, E.A. Royzman, A. Gaudig, A.R. Garan, V.K. Topkara, H. Takayama, K. Takeda, Y. Naka, M. Yuzefpolskaya, P.C. Colombo Source Type: research

Laterality of Cerebral Artery Hemodynamics in Continuous-Flow LVAD Patients: A Pilot Study in Relation to Stroke
A predominance of ischemic stroke in the right hemisphere among patients with continuous-flow left ventricular assist device (LVAD) support has been noted. The reasons for this clinical presentation are unknown, though others have hypothesized greater blood flow to the right common carotid artery. Since arterial pulsatility and blood velocity (as a surrogate for flow) have been associated with cerebrovascular complications, we hypothesized that significant differences in the pulsatility and/or Vmax of the left and right middle cerebral artery may be present in LVAD patients.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: E.J. St öhr, A. Gaudig, A. Pinsino, F. Castagna, P.C. Colombo, M. Yuzefspolskaya, A.R. Garan, V.K. Topkara, H. Takayama, K. Takeda, Y. Naka, J.R. Cockroft, B.J. McDonnell, J.Z. Willey Source Type: research

Utility of Hypercoagulable Work-Up in Predicting Post-Operative Complications in Total Artificial Heart (TAH) Implant Patients
Since 2012, our center has used TAH as bridge to transplant or as destination therapy. Despite antithrombotic prophylactic therapy for the prevention of post implant thromboembolic stroke, the thrombotic causes of adverse events and death remain virtually unknown. In efforts to objectively assess hemostasis, our center uses thromboelastograph platelet mapping (TEG-PM) pre-post implant to guide therapy. The purpose of this study was to assess the predictability of the baseline thrombophilia and TEG-PM work-up parameters with development hematological adverse events after TAH implantation.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: O. Volod, B. Coleman, L.D. Lam, M. Pollack, D. Collier, R. Lee, D. Mochizuki, L.S. Czer, J. Moriguchi, J.A. Kobashigawa, F.A. Arabia Source Type: research

Donor Right Ventricular Stroke Work Index (RVSWI) is a Poor Predictor of Primary Graft Dysfunction (PGD) After Heart Transplantation
PGD manifests as ventricular dysfunction of the implanted heart within 24 hours of transplantation. It is the leading cause of 30-day mortality after heart transplantation. Donor risk factors have been identified from several studies. Our aim was to study the association between donor RVSWI and recipient PGD.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: S. Das De, S. Avtaar Singh, J. Dalzell, H. Doshi, P. Curry, N. Al-Attar, S. Nair Source Type: research

PAPi Shows a Stronger Correlation With RAP versus RVSWI in Both HFrEF and HFpEF
This study compares the correlation of RAP with PAPi and RVSWI in patients with heart failure with reduced EF (HFrEF) and those with preserved EF (HFpEF).
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: N. Nair, S. Yang, C. Marzbani, L. Truong, E. Gongora Source Type: research

Stroke Patterns and Implications for Ventricular Functional Remodeling in Left Ventricular Assist Systems
Ischemic stroke-related complications (particularly in the right hemisphere) are frequently encountered with Left Ventricular Assist Systems (LVAS). The neuro-cardiac axis may influence ventricular remodeling. However it remains unknown if stroke patterns are related to ventricular remodeling after facilitated hemodynamic support with LVAS. We hypothesized that strokes occurring in the right hemisphere, within the insula region, may enhance left ventricular remodeling through unopposed activation of the left insular region.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: D.F. Snipelisky, P. Ivak, G. Stewart, M. Givertz, M. Pfeffer, J. Groarke, S. Singh, I. Netuka, M. Mehra Source Type: research

Cardiovascular Magnetic Resonance Imaging for Risk Assessment and Prediction of Clinical Worsening in Pulmonary Arterial Hypertension
To determine the clinically detectable changes of right ventricular (RV) volume and stroke volume (SV) that predicts clinical worsening in patients with pulmonary arterial hypertension (PAH).
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: C. G öransson, N. Vejlstrup, J. Carlsen Source Type: research

A Co-Rhythmic, Isolable, Self-Maintenance, Assist (CoRISMA) Device for Class III Heart Failure
Mechanical circulatory support for class III heart failure will be acceptable if it is devoid of any adverse events associated with current LVAD devices. Long blood paths, lack of regular maintainence in a pump bathed in blood and tethered operation may account for some of the adverse events witnessed in current LVADs such as stroke, pump thrombosis and infections. An intra-cardiac device with ability to isolate and clean the interior of the pump, powered without driveline is presented.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: J. Park, P. Bonde Source Type: research

Strategy for Surgical Correction and Mitigation of Outflow Graft Twist with a Centrifugal-Flow Left Ventricular Assist System
A fully magnetically levitated centrifugal-flow left ventricular assist system (LVAS) has been introduced with demonstration of improved hemocompatibility, reduced rates of pump malfunction and stroke.1 –4 This LVAS, the HeartMate 3 (Abbott, IL, USA) pump, has been observed to have isolated cases of an outflow graft twist occurring in follow-up periods, later in the course of support.1,5 The mechanism for this development is incompletely understood, however it may be related to the proximal outfl ow graft metallic swivel joint that allows relatively free rotation of this graft once implanted (Figure 1), which is designed...
Source: The Journal of Heart and Lung Transplantation - March 22, 2018 Category: Transplant Surgery Authors: Evgenij V. Potapov, Ivan Netuka, Friedrich Kaufmann, Volkmar Falk, Mandeep R. Mehra Source Type: research

Strategy for surgical correction and mitigation of outflow graft twist with a centrifugal-flow left ventricular assist system
A fully magnetically levitated centrifugal-flow left ventricular assist system (LVAS) has been introduced, with demonstration of improved hemocompatibility and reduced rates of pump malfunction, and stroke.1 –4 This LVAS, the HeartMate 3 (Abbott, Abbott Park, IL) pump, has been observed to have isolated cases of an outflow graft twist occurring in follow-up periods, later in the course of support.1,5 The mechanism for this development is incompletely understood. It may, however, be related to the prox imal outflow graft metallic swivel joint that allows relatively free rotation of this graft once implanted (Figure 1), wh...
Source: The Journal of Heart and Lung Transplantation - March 22, 2018 Category: Transplant Surgery Authors: Evgenij V. Potapov, Ivan Netuka, Friedrich Kaufmann, Volkmar Falk, Mandeep R. Mehra Tags: Research Correspondence Source Type: research