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Rapid target allopurinol concentrations in the hypoxic fetus after maternal administration during labour
Conclusions A dose of 500 mg intravenous allopurinol rapidly crosses the placenta and provides target concentrations in 95% of the fetuses at the moment of delivery, which makes it potentially useful as a neuroprotective agent in perinatology with very little side effects. Trial registration The study is registered in the Dutch Trial Register (NTR1383) and the Clinical Trials protocol registration system (NCT00189007).
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 13, 2014 Category: Perinatology & Neonatology Authors: Kaandorp, J. J., van den Broek, M. P. H., Benders, M. J. N. L., Oudijk, M. A., Porath, M. M., Bambang Oetomo, S., Wouters, M. G. A. J., van Elburg, R., Franssen, M. T. M., Bos, A. F., Mol, B. W. J., Visser, G. H. A., van Bel, F., Rademaker, C. M. A., Derk Tags: Stroke, Medicines regulation Original articles Source Type: research

When angels catch us – Madeline ’ s hysterectomy story
How do we know there are angels? Do we have our own special guardian angels watching over us? How many times have we almost entered into danger only to change our minds at the last minute? Is this simply being lucky or has there been an unconscious inner voice warning us? I have truly believed for a long time that there are God’s angels watching over us and over the years there have been occasions when I have had warnings of some impending doom and thankfully avoided tragedy. Sometimes I’ve just had feelings or a “sixth sense” and the negative event still happened but somehow I had felt that premonition. Wa...
Source: The Hysterectomy Association - April 27, 2012 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health hysterectomy stories Source Type: news

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