• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

In-hospital Mortality and Stroke Following Surgical Aortic Valve Replacement: A Nationwide Perspective
Stroke is a widely recognized complication following aortic valve replacement (AVR), especially among elderly patients. Significant heterogeneity exists in the current literature around the actual incidence of stroke following AVR among high-risk patients. Our objective was to define risk of stroke in patients undergoing surgical AVR from a large national database.
Source: The Journal of Thoracic and Cardiovascular Surgery - June 4, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Shikhar Agarwal, Aatish Garg, Akhil Parashar, Lars G. Svensson, E. Murat Tuzcu, Jose Navia, Stephanie Mick, Samir R. Kapadia Source Type: research

In-hospital mortality and stroke after surgical aortic valve replacement: A nationwide perspective
Stroke is a widely recognized complication after aortic valve replacement (AVR), especially among elderly patients. The literature contains substantial variability in reports of the actual incidence of stroke after AVR among high-risk patients. Our objective was to define risk of stroke in patients undergoing surgical AVR, using a large national database.
Source: The Journal of Thoracic and Cardiovascular Surgery - June 4, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Shikhar Agarwal, Aatish Garg, Akhil Parashar, Lars G. Svensson, E. Murat Tuzcu, Jose L. Navia, Stephanie Mick, Samir R. Kapadia Tags: Acquired cardiovascular disease Source Type: research

Atheromatous disease of the aorta and perioperative stroke
Despite continued improvements in patient outcomes after cardiac surgery, stroke remains one of the most feared and devastating complications of cardiac surgery and is estimated to occur in 1.2% to 1.6% of patients undergoing coronary artery bypass grafting (CABG).1-3 The incidence of stroke increases for other common cardiac surgical procedures, and contemporary studies from the Society of Thoracic Surgeons database have reported perioperative stroke rates of 1.4% for mitral valve repair,4 1.5% for aortic valve replacement,5 2.1% for mitral valve replacement,4 and 6.6% for proximal aorta replacement.
Source: The Journal of Thoracic and Cardiovascular Surgery - September 13, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Nicholas D. Andersen, Stephen A. Hart, Ganesh P. Devendra, Esther S.H. Kim, Douglas R. Johnston, Jacob N. Schroder, Richard A. Krasuski Tags: Expert review Source Type: research

Balloons are not for angioplasty alone: A novel occlusion technique for stroke prevention
Stroke remains a significant source of morbidity and mortality after thoracic endovascular aortic repair (TEVAR). This is especially true with “hybrid” aortic arch aneurysm repairs, with stroke rates as high as 8% reported previously.1 Many of these patients have significant medical comorbidities, including previous stroke, peripheral vascular, and coronary artery disease, and resultant aortic atheroma and calcifications. It is well kn own that endovascular procedures in the aortic arch result in significant cerebral embolization; in fact, in the SENTINEL trial evaluating transcatheter cerebral embolic protection devic...
Source: The Journal of Thoracic and Cardiovascular Surgery - November 2, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Christopher R. Burke, Pavan Atluri Tags: Editorial Commentary Source Type: research

Commentary: Balloons are not for angioplasty alone: A novel occlusion technique for stroke prevention
Stroke remains a significant source of morbidity and mortality after thoracic endovascular aortic repair (TEVAR). This is especially true with “hybrid” aortic arch aneurysm repairs, with stroke rates as high as 8% reported previously.1 Many of these patients have significant medical comorbidities, including previous stroke, peripheral vascular, and coronary artery disease, and resultant aortic atheroma and calcifications. It is well kn own that endovascular procedures in the aortic arch result in significant cerebral embolization; in fact, in the SENTINEL trial evaluating transcatheter cerebral embolic protection devic...
Source: The Journal of Thoracic and Cardiovascular Surgery - November 1, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Christopher R. Burke, Pavan Atluri Tags: Commentary Source Type: research

Measuring and mitigating stroke in transcatheter aortic valve implantation: Long roads to the easy answers
Transcatheter aortic valve implantation (TAVI) has rapidly displayed its utility in the treatment of aortic valve disease. While presenting a lesser procedural morbidity and mortality risk, as compared with surgical aortic valve replacement (SAVR), early trials reported higher rates of stroke.1,2 To mitigate this complication, cerebral embolic protection (CEP) devices were developed for use in TAVI but there has been limited penetrance into the market. Among the reasons for this are their novelty, relatively low rates of clinically relevant stroke, added complexity of their deployment, cost, and uncertainty of their benefit.
Source: The Journal of Thoracic and Cardiovascular Surgery - February 12, 2017 Category: Cardiovascular & Thoracic Surgery Authors: John Bozinovski Tags: Editorial commentary Source Type: research

Performance of CHA2DS2-VASc Score for Stroke Prediction after Surgical Aortic Valve Replacement
Stroke is a frequent complication occurring early and late after surgical aortic valve replacement (SAVR). There is an unmet clinical need for simple tools to assess postoperative stroke risk. We sought to assess the predictive performance of CHA2DS2-VASc score in patients undergoing SAVR with a bioprosthesis.
Source: The Journal of Thoracic and Cardiovascular Surgery - July 28, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Tuomas Kiviniemi, Joonas Lehto, Maunu Nissinen, Tuomo Nieminen, Juha Hartikainen, Markus Malmberg, Fredrik Yannopoulos, Jyri Savolainen, Pasi Karjalainen, K E Juhani Airaksinen, Stefano Rosato, Fausto Biancari Source Type: research

The Impact of Perioperative Stroke and Delirium on Outcomes after Surgical Aortic Valve Replacement
The effects of stroke and delirium on post-discharge cognition and patient-centered health outcomes after surgical aortic valve replacement (SAVR) are not well characterized. Here we assess the impact of post-operative stroke and delirium on these health outcomes in SAVR patients at 90 days.
Source: The Journal of Thoracic and Cardiovascular Surgery - March 18, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Steven R. Mess é, Jessica R. Overbey, Vinod H. Thourani, Alan J. Moskowitz, Annetine C. Gelijns, Mark A. Groh, Michael J. Mack, Gorav Ailawadi, Karen L. Furie, Andrew M. Southerland, Michael L. James, Claudia Scala Moy, Lopa Gupta, Pierre Voisine, Louis Source Type: research

Outcomes of surgical aortic valve replacement for severe aortic stenosis: Incorporation of left ventricular systolic function and stroke volume index
We sought to a) assess predictors of mortality in consecutive patients with severe aortic stenosis (AS) undergoing aortic valve replacement (AVR) and b) determine if there are differences in mortality, separated on the basis of different AS subtypes and left ventricular stroke volume index (LV-SVI).
Source: The Journal of Thoracic and Cardiovascular Surgery - March 11, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Roosha Parikh, Andrew L. Goodman, Tyler Barr, Joseph F. Sabik, Lars G. Svensson, L Leonardo Rodriguez, Bruce W. Lytle, Richard A. Grimm, Brian P. Griffin, Milind Y. Desai Source Type: research

Inter- and Intra-site Variability of Mortality and Stroke for Sites Performing both Surgical and Transcatheter Aortic Valve Replacement for Aortic Valve Stenosis in Intermediate-risk Patients
Multi-site procedure-based randomized trials may be confounded by performance variability and variability among sites. Therefore, we studied variability in mortality and stroke after patients were randomized to surgical (SAVR) or transcatheter aortic valve replacement (TAVR) in PARTNER-2A.
Source: The Journal of Thoracic and Cardiovascular Surgery - June 14, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Kevin L. Greason, Eugene H. Blackstone, Jeevanantham Rajeswaran, Ashley M. Lowry, Lars G. Svensson, John G. Webb, E.Murat Tuzcu, Craig R. Smith, Raj R. Makkar, Michael J. Mack, Vinod H. Thourani, Susheel K. Kodali, Martin B. Leon, D.Craig Miller Source Type: research

Inter- and intrasite variability of mortality and stroke for sites performing both surgical and transcatheter aortic valve replacement for aortic valve stenosis in intermediate-risk patients
Multisite procedure-based randomized trials may be confounded by performance variability and variability among sites. Therefore, we studied variability in mortality and stroke after patients were randomized to surgical (SAVR) or transcatheter aortic valve replacement (TAVR) in the Placement of Aortic Transcatheter Valves-2A (PARTNER-2A) randomized trial.
Source: The Journal of Thoracic and Cardiovascular Surgery - June 14, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Kevin L. Greason, Eugene H. Blackstone, Jeevanantham Rajeswaran, Ashley M. Lowry, Lars G. Svensson, John G. Webb, E. Murat Tuzcu, Craig R. Smith, Raj R. Makkar, Michael J. Mack, Vinod H. Thourani, Susheel K. Kodali, Martin B. Leon, D. Craig Miller Tags: Adult Source Type: research

Control of ventricular unloading using an electrocardiogram-synchronized Thoratec paracorporeal ventricular assist device
Conclusions: The timing of pump ejection in synchronized mode yields control over left ventricular energetics and can be a method to achieve gradual reloading of a recoverable left ventricle. The traditionally suggested counterpulsation is not optimal in ventriculo-aortic cannulation when maximum unloading is desired.
Source: The Journal of Thoracic and Cardiovascular Surgery - January 14, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Raffael Amacher, Alberto Weber, Henriette Brinks, Shannon Axiak, Antonio Ferreira, Lino Guzzella, Thierry Carrel, James Antaki, Stijn Vandenberghe Tags: Evolving Technology/Basic Science Source Type: research

The impact of unilateral versus bilateral antegrade cerebral perfusion on surgical outcomes after aortic arch replacement: A propensity-matched analysis
Conclusions: Using unilateral antegrade cerebral perfusion in a pressure-controlled manner during mild systemic hypothermia is a safe protection strategy in elective aortic arch surgery, associated with similar morbidity and mortality in comparison with bilateral antegrade cerebral perfusion, even if total arch replacement is required. Bilateral antegrade cerebral perfusion reveals a trend of higher incidence of stroke, probably due to manipulation on the arch vessels.
Source: The Journal of Thoracic and Cardiovascular Surgery - January 6, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Andreas Zierer, Petar Risteski, Ali El-Sayed Ahmad, Anton Moritz, Anno Diegeler, Paul P. Urbanski Tags: Acquired Cardiovascular Disease Source Type: research

The effect of the Cox-maze procedure for atrial fibrillation concomitant to mitral and tricuspid valve surgery
Objectives: Atrial fibrillation (AF) is associated with less favorable outcomes in patients undergoing mitral valve and tricuspid valve surgery. Despite growing evidence on the potential benefits of surgical ablation for AF there is significant variability among surgeons in treatment of AF. The purpose of our study was to assess the effect of the Cox-maze procedure on operative and follow-up outcomes.Methods: In our prospective study, patients who underwent isolated mitral valve or mitral valve+tricuspid valve surgery without history of AF (n = 506), with untreated AF (n = 75), or with Cox-maze procedure (n = 236) we...
Source: The Journal of Thoracic and Cardiovascular Surgery - September 30, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Niv Ad, Sari D. Holmes, Paul S. Massimiano, Graciela Pritchard, Lori E. Stone, Linda Henry Tags: Acquired Cardiovascular Disease Source Type: research

Impact of concurrent surgical valve procedures in patients receiving continuous-flow devices
Conclusions: Patients frequently require concurrent VPs at the time of LVAD placement; these patients are sicker and have higher early mortality. Furthermore, right ventricular dysfunction is increased in these patients. Further studies to develop selection criteria for concurrent valve interventions are important to further improve clinical outcomes.
Source: The Journal of Thoracic and Cardiovascular Surgery - January 14, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Ranjit John, Yoshifumi Naka, Soon J. Park, Chittoor Sai-Sudhakar, Christopher Salerno, Kartik S. Sundareswaran, David J. Farrar, Carmelo A. Milano Tags: Acquired Cardiovascular Disease Source Type: research

Pages: 1  2  3  4