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074-i * off-pump coronary artery bypass reduces early stroke in octogenarians: a meta-analysis of 18,000 patients
Conclusion: Coronary artery bypass in octogenarians can be performed with low early mortality. Number of grafts is lesser in the OPCABG cohort. While stroke rates are higher with conventional surgery, all other adverse events are comparable. Future randomised trials are needed to define the role of off-pump surgery in this high-risk cohort.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Altarabsheh, S. E., Deo, S., Rabab'h, A., Sharma, V., Lim, J. Y., Cho, Y. H., Park, S. J. Tags: Adult cardiac rapid response 1 Source Type: research

262 * changes in cerebral oximetry and haemodynamics during off-pump coronary artery bypass: mechanism for perioperative stroke?
Conclusion: Cerebral oxygenation may be impaired during OPCAB with delayed recovery by closure despite normalisation of cardiac output. This prolonged desaturation was not artefactual or related to patient posture. We recommend the routine monitoring of cerebral oximetry during OPCAB to prevent brain injury.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Al-Badawi, T., Witts, S., Howell, L., Richards, R., Rozario, C., Hartley, M., Tang, A. Tags: Developments in coronary artery bypass graft Source Type: research

Red blood cell transfusion is a determinant of neurological complications after cardiac surgery
CONCLUSIONS Transfusion of more than 2 units of RBCs after cardiac surgery is associated with a significantly increased risk of postoperative stroke and TIA.
Source: Interactive CardioVascular and Thoracic Surgery - January 20, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Mariscalco, G., Biancari, F., Juvonen, T., Zanobini, M., Cottini, M., Banach, M., Murphy, G. J., Beghi, C., Angelini, G. D. Tags: Electrophysiology - arrhythmias Adult Cardiac Source Type: research

A multicentre Spanish study for multivariate prediction of perioperative in-hospital cerebrovascular accident after coronary bypass surgery: the PACK2 score
CONCLUSIONS PACK2 risk scale shows good predictive accuracy in the data analysed and could be useful in clinical practice for decision making and patient selection.
Source: Interactive CardioVascular and Thoracic Surgery - July 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Hornero, F., Martin, E., Rodriguez, R., Castella, M., Porras, C., Romero, B., Maroto, L., Perez De La Sota, E., on behalf of the Working Group on Arrhythmia Surgery and Cardiac Pacing of the Spanish Society for Cardiovascular and Thoracic Surgery (SECTCV) Tags: Adult Cardiac Source Type: research

HEARTSTRING enabled no-touch proximal anastomosis for off-pump coronary artery bypass grafting: current evidence and technique
Surgical revascularization remains the standard of care for many patients. Off-pump coronary artery bypass grafting (OPCAB) without cardiopulmonary bypass (CPB) has evolved during the past 20 years, and as such can significantly reduce the occurrence of neurological complications. While avoiding the aortic cross-clamping required in conventional on-pump techniques, OPCAB results in a lower incidence of stroke. However, clamp-related risk of stroke remains if partial or side-biting clamps are applied for proximal anastomoses. Others and we have demonstrated that no-touch ‘anaortic’ approaches avoiding any clampi...
Source: Interactive CardioVascular and Thoracic Surgery - August 16, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Emmert, M. Y., Grunenfelder, J., Scherman, J., Cocchieri, R., van Boven, W.-J. P., Falk, V., Salzberg, S. P. Tags: Coronary Source Type: research

Results of surgical aortic valve replacement and transapical transcatheter aortic valve replacement in patients with previous coronary artery bypass grafting
CONCLUSIONS Reported differences in mortality and morbidity after TaTAVR and RAVR reflect differences in baseline risk profiles. Given the lower trend for renal complications, patients at higher perioperative renal risk might be better served by TaTAVR.
Source: Interactive CardioVascular and Thoracic Surgery - May 25, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Onorati, F., D'Onofrio, A., Biancari, F., Salizzoni, S., De Feo, M., Agrifoglio, M., Mariscalco, G., Lucchetti, V., Messina, A., Musumeci, F., Santarpino, G., Esposito, G., Santini, F., Magagna, P., Beghi, C., Aiello, M., Ratta, E. D., Savini, C., Troise, Tags: Molecular biology, Transplantation - heart, Basic research vascular Adult Cardiac Source Type: research

055 * simultaneous hybrid carotid stenting and coronary bypass surgery versus concomitant open carotid and coronary bypass surgery: a pilot feasibility study
Conclusions: Our results show that the hybrid procedure of carotid stenting and coronary surgery might be a good therapeutic option for this high-risk population of patients. Further, extended studies are needed to assess the proper value of this procedure.
Source: Interactive CardioVascular and Thoracic Surgery - September 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Micovic, S., Sagic, D., Boskovic, S., Radak, D., Milojevic, P., Nezic, D., Dokic, O., Dukanovic, B. Tags: Controversies in coronary artery surgery II Source Type: research

Should patients with asymptomatic significant carotid stenosis undergo simultaneous carotid and cardiac surgery?
This study included patients with unilateral severe (>70%) asymptomatic carotid stenosis requiring CABG. An earlier partly randomized trial also showed better outcomes for patients undergoing simultaneous procedures (P = 0.045). Interestingly, systematic reviews previously failed to show compelling evidence supporting prophylactic CEA. This could be partly due to the fact that these reviews collectively analyse different cohort qualities. Neurological studies have, however, shown reduced cognitive and phonetic quality and function in patients with unilateral and bilateral asymptomatic carotid artery stenosis. Twenty-one...
Source: Interactive CardioVascular and Thoracic Surgery - March 17, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Ogutu, P., Werner, R., Oertel, F., Beyer, M. Tags: Adult Cardiac Source Type: research

044 * open aortic arch replacement in high risk patients: the gold standard
Conclusion: Open TAR can be performed with low mortality and morbidity and excellent long-term results even in high-risk patients. Total endovascular repair may represent an option for patients not suitable for open surgery.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Iafrancesco, M., Ranasinghe, A., Dronavalli, V., Adam, D., Claridge, M., Riley, P., McCafferty, I., Mascaro, J. Tags: Part I: Aortic arch interventions: Debranching, rebranching, stenting and beyond Source Type: research

Meta-analysis of three randomized controlled trials comparing coronary artery bypass grafting with percutaneous coronary intervention using drug-eluting stenting in patients with diabetes
CONCLUSIONS In patients with diabetes, PCI was associated with no difference in death and MI at 1 year. However, at 5 years, PCI was associated with a higher incidence of death and MI. PCI was associated with a higher incidence of RRV but a lower incidence of stroke.
Source: Interactive CardioVascular and Thoracic Surgery - November 22, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Fanari, Z., Weiss, S. A., Zhang, W., Sonnad, S. S., Weintraub, W. S. Tags: Molecular biology Adult Cardiac Source Type: research

054 * hybrid surgery in patients with concomitant critical coronary and carotid artery lesions
Conclusions: Hybrid surgery in patients with concomitant critical coronary and carotid artery lesions is a safe and very effective procedure that reduces the number of complications during the surgical treatment of this severe cohort of patients.
Source: Interactive CardioVascular and Thoracic Surgery - September 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Edemskiy, A., Chernyavskiy, A., Vinogradova, T. E., Chernyavskiy, M. Tags: Controversies in coronary artery surgery II Source Type: research

151 * comparison of intermittent cold versus intermittent warm blood cardioplegia in 2200 adult cardiac surgery patients
Conclusions: In elective cardiac surgery, there was no difference in clinical outcome between cold and warm blood cardioplegia. In emergency patients, however, with most of them operated on in acute coronary syndrome, warm cardioplegia might be an option to improve outcome.
Source: Interactive CardioVascular and Thoracic Surgery - September 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Trescher, K., Gleiss, A., Boxleitner, M., Dietl, W., Kassal, H., Holzinger, C., Podesser, B. Tags: Cardiac potpourri Source Type: research

183 * the use of bilateral internal thoracic arteries increases long-term survival in elderly patients: a propensity-matched analysis
Conclusions: The use of bilateral thoracic arteries improves the long-term survival after CABG, but increases the risk of postoperative sternal wound complications. A more extensive use in the elderly population should be advocated, but only in selected patients with low risk of sternal complications.
Source: Interactive CardioVascular and Thoracic Surgery - September 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Pettinari, M., Meuris, B., Sergeant, P. Tags: Arterial revascularization Source Type: research

228 * minimally invasive direct coronary bypass grafting versus percutaneous coronary intervention for single-vessel disease: a systematic review with meta-analysis of 2731 patients
Conclusions: The present systematic review underscores the superiority of MIDCAB over PCI for the treatment of single-vessel disease of the LAD.
Source: Interactive CardioVascular and Thoracic Surgery - September 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Deppe, A. C., Liakopoulos, O. J., Kuhn, E. W., Slottosch, I., Scherner, M., Rahmanian, P., Choi, Y., Wahlers, T. Tags: Coronary artery bypass grafting II Source Type: research

232 * early anticoagulation therapy after bioprosthetic aortic valve implantation: comparing warfarin versus aspirin
Conclusions: This is to date the largest randomized trial comparing warfarin to aspirin as early anticoagulation therapy after implantation of bioprosthetic aortic valves. The results are not conclusive, but aspirin therapy seems as safe as warfarin therapy, and with significantly fewer gastrointestinal bleeding events, three months after surgery.
Source: Interactive CardioVascular and Thoracic Surgery - September 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Rafiq, S., Steinbruchel, D. A., Moeller, C. H., Lund, J., Thiis, J. J., Koeber, L., Lilleoer, N. B., Olsen, P. S. Tags: Decision-making in aortic valve repair Source Type: research

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