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Specialty: Orthopaedics
Source: Journal of Bone and Mineral Research

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Total 25 results found since Jan 2013.

Impact of stroke history on the risk of recurrent hip fracture or major osteoporotic fractures among patients with incident hip fracture. A nationwide cohort study
In conclusion, stroke history was associated with slightly higher risk of recurrent fracture among patients with first-time hip fracture in the overall analysis, although the confidence interval included a null result. The association was modified by baseline mobility: Pati ents with stroke history and good mobility had a markedly higher risk, whereas patients with stroke and poor mobility did not.This article is protected by copyright. All rights reserved.
Source: Journal of Bone and Mineral Research - December 19, 2022 Category: Orthopaedics Authors: Thomas J. Hjelholt, S øren P. Johnsen, Peter K. Brynningsen, Grethe Andersen, Alma B. Pedersen Tags: Research Article Source Type: research

Hip fracture, comorbidity, and the risk of myocardial infarction and stroke: A Danish nationwide cohort study, 1995 ‐2015
This article is protected by copyright. All rights reserved
Source: Journal of Bone and Mineral Research - August 21, 2017 Category: Orthopaedics Authors: Alma B. Pedersen, Vera Ehrenstein, Szimonetta K. Sz épligeti, Henrik T. Sørensen Tags: Original Article Source Type: research

Higher Dietary Calcium Intakes are Associated With Reduced Risks of Fractures, Cardiovascular Events and Mortality: A Prospective Cohort Study of Older Men and Women
This article is protected by copyright. All rights reserved
Source: Journal of Bone and Mineral Research - March 31, 2015 Category: Orthopaedics Authors: Belal Khan, Caryl A. Nowson, Robin M. Daly, Dallas R. English, Allison M. Hodge, Graham G. Giles, Peter R. Ebeling Tags: Original Article Source Type: research

Estimating the incidence and key risk factors of cardiovascular disease in patients at high risk of imminent fracture using routinely collected real ‐world data from the UK
This article is protected by copyright. All rights reserved.
Source: Journal of Bone and Mineral Research - July 12, 2022 Category: Orthopaedics Authors: Marta Pineda ‐Moncusí, Leena El‐Hussein, Antonella Delmestri, Cyrus Cooper, Moayyeri Alireza, Cesar Libanati, Emese Toth, Daniel Prieto‐Alhambra, Sara Khalid Tags: Research Article Source Type: research

Risk of Incident Atrial Fibrillation With Zoledronic Acid Versus Denosumab: A Propensity Score –Matched Cohort Study
ABSTRACTZoledronic acid (ZA) is an effective agent in osteoporosis and malignancy ‐related bone disease but may be associated with increased risk of atrial fibrillation (AF), although current studies disagree on this risk. To examine the risk of incident AF among patients receiving ZA compared with denosumab in the first year of treatment, we performed a new‐user, active comp arator cohort study including privately insured Americans between January 1, 2010, and June 30, 2019. Individuals aged ≥50 years without known arrhythmia or advanced kidney disease who initiated ZA were 1:1 propensity score (PS)‐matched to i...
Source: Journal of Bone and Mineral Research - November 2, 2020 Category: Orthopaedics Authors: Kristin M D'Silva, Sara Jane Cromer, Elaine W Yu, Michael Fischer, Seoyoung C Kim Tags: Original Article Source Type: research

Sclerostin down ‐regulation globally by naturally occurring genetic variants, or locally in atherosclerotic plaques, does not associate with cardiovascular events in humans
This article is protected by copyright. All rights reserved.
Source: Journal of Bone and Mineral Research - March 19, 2021 Category: Orthopaedics Authors: Gill Holdsworth, James R Staley, Peter Hall, Ian van Koeverden, Ciara Vangjeli, Remi Okoye, Rogely Waite Boyce, James R Turk, Martin Armstrong, Alison Wolfreys, Gerard Pasterkamp Tags: Original Article Source Type: research

Sclerostin Downregulation Globally by Naturally Occurring Genetic Variants, or Locally in Atherosclerotic Plaques, Does Not Associate With Cardiovascular Events in Humans
ABSTRACTInhibition of sclerostin increases bone formation and decreases bone resorption, leading to increased bone mass, bone mineral density, and bone strength and reduced fracture risk. In a clinical study of the sclerostin antibody romosozumab versus alendronate in postmenopausal women (ARCH), an imbalance in adjudicated serious cardiovascular (CV) adverse events driven by an increase in myocardial infarction (MI) and stroke was observed. To explore whether there was a potential mechanistic plausibility that sclerostin expression, or its inhibition, in atherosclerotic (AS) plaques may have contributed to this imbalance,...
Source: Journal of Bone and Mineral Research - March 30, 2021 Category: Orthopaedics Authors: Gill Holdsworth, James R Staley, Peter Hall, Ian Koeverden, Ciara Vangjeli, Remi Okoye, Rogely W Boyce, James R Turk, Martin Armstrong, Alison Wolfreys, Gerard Pasterkamp Tags: Original Article Source Type: research

Calcium Supplements Increase Risk of Myocardial Infarction
Abstract The cardiovascular safety of calcium supplements has been revisited with a further meta‐analysis,(1) which concludes that calcium supplementation does not increase coronary heart disease in women, without providing data for men. Their conclusion is at odds with that of our meta‐analyses, which reported that calcium increased the risk of myocardial infarction (MI) and possibly stroke in men and women together.(2,3)There are important differences between approaches to the meta‐analyses. In the current paper and previously, the authors suggest that including men and self‐reported events may have explained the...
Source: Journal of Bone and Mineral Research - September 11, 2014 Category: Orthopaedics Authors: Mark J Bolland, Andrew Grey, Alison Avenell, Ian R Reid Tags: Letter to the Editor Source Type: research

Retraction: ‘Beneficial Effect of Intermittent Cyclical Etidronate Therapy in Hemiplegic Patients Following an Acute Stroke’ by Y. Sato, T. Asoh, M. Kaji and K. Oizumi
The above article, published online on 1 December 2000 in Wiley Online Library (wileyonlinelibrary.com), and in Volume 15, Issue 12, pages 2487–2494, has been retracted by agreement between the authors, the Journal Editor in Chief, Juliet Compston, and Wiley Periodicals, Inc. The retraction has been agreed due to concerns about the underlying data to which the authors have given no satisfactory response. Dr Sato acknowledges that his co‐authors are named as such for honorary reasons and are not responsible for the content of the manuscript.ReferenceSato, Y., Asoh, T., Kaji, M. and Oizumi, K. (2000) Beneficial Effect of...
Source: Journal of Bone and Mineral Research - August 31, 2016 Category: Orthopaedics Tags: Retraction Source Type: research

Comparative Safety and Effectiveness of Denosumab Versus Zoledronic Acid in Patients With Osteoporosis: A Cohort Study
This article is protected by copyright. All rights reserved
Source: Journal of Bone and Mineral Research - October 12, 2016 Category: Orthopaedics Authors: Nam ‐Kyong Choi, Daniel H. Solomon, Theodore N. Tsacogianis, Joan E. Landon, Hong Ji Song, Seoyoung C. Kim Tags: Original Article Source Type: research

Risk and prevention of fracture in patients with major medical illnesses: A mini ‐review
This article is protected by copyright. All rights reserved
Source: Journal of Bone and Mineral Research - November 3, 2016 Category: Orthopaedics Authors: Steven R. Cummings, Richard Eastell Tags: Review Source Type: research