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Hemorrhagic Transformation and Stroke Recurrence in Children with Cardiac Disease Receiving Antithrombotic Therapy for Secondary Stroke Prevention
CONCLUSIONS: In spite of the 24% hemorrhagic transformation rate, antithrombotic therapy has a positive risk-balance in certain cardioembolic stroke subgroups, particularly in those with single-ventricle physiology, when accounting for stroke volume.PMID:34152075 | DOI:10.1111/jth.15428
Source: Thrombosis and Haemostasis - June 21, 2021 Category: Hematology Authors: Elizabeth Pulcine Mike Seed Leonardo R Brand ão Mahmoud Slim Sunitha Palasamudram Manohar Shroff Mahendranath Moharir Gabrielle deVeber Nomazulu Dlamini Source Type: research

Adverse consequences of immediate thrombolysis-related complications: a multi-centre registry-based cohort study of acute stroke
In conclusion, the risk of nosocomial infections, worsening of stroke severity, longer HASU stay, disability and death is increased following immediate TRC. The management of patients following immediate TRC is more complex than previously thought and such complexity needs to be considere d when planning an increased thrombolysis service.
Source: Journal of Thrombosis and Thrombolysis - July 13, 2021 Category: Hematology Source Type: research

Patterns of thromboembolism in patients with advanced pancreatic cancer undergoing 1st-line chemotherapy with FOLFIRINOX or Gemcitabine/nab-paclitaxel
CONCLUSION: Patients with aPC undergoing palliative 1st-line chemotherapy with FOLFIRINOX or GN face a high risk for VTE/ATE and its diagnosis is linked to worse clinical outcomes. VTE-risk prediction models have limited ability to sub-stratify thrombotic events in this high-risk scenario.PMID:34255340 | DOI:10.1055/a-1548-4847
Source: Thrombosis and Haemostasis - July 13, 2021 Category: Hematology Authors: Jakob M Riedl Esther Schwarzenbacher Florian Moik Lena Horvath Antonia Gantschnigg Felix Renneberg Florian Posch Dominik A Barth Michael Stotz Martin Pichler Stefan Hatzl Simon Fandler-H öfler Paul Gressenberger Thomas Gary Philipp Jost Richard Greil Cih Source Type: research