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Specialty: Hematology
Source: Thrombosis Research
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Total 221 results found since Jan 2013.
Thromboelastography as a predictor of functional outcome in acute ischemic stroke patients undergoing endovascular treatment
Thromboelastography (TEG) is a useful for predicting hemorrhagic transformation, early neurological deterioration, and functional outcome after stroke. We aimed to investigate whether TEG value could also be useful in predicting functional outcome via various intraprocedural and postprocedural factors in patients with acute large vessel occlusive stroke who underwent intraarterial thrombectomy (IAT).
Source: Thrombosis Research - March 31, 2023 Category: Hematology Authors: Jae-Chan Ryu, Seunguk Jung, Jae-Han Bae, Sang Hee Ha, Bum Joon Kim, Sang-Beom Jeon, Dong-Wha Kang, Sun U. Kwon, Jong S. Kim, Jun Young Chang Tags: Full Length Article Source Type: research
D-dimer to fibrinogen ratio predicts early neurological deterioration in ischemic stroke with atrial fibrillation
The D-dimer to fibrinogen ratio (DFR) is a good indicator of clot-producing activity in thrombotic disease, but its clinical usefulness in stroke patients with nonvalvular atrial fibrillation (NVAF) has not been studied. We evaluated the association between the DFR and early neurological deterioration (END) in acute ischemic stroke (AIS) patients with NVAF.
Source: Thrombosis Research - July 31, 2023 Category: Hematology Authors: Ki-Woong Nam, Chi Kyung Kim, Sungwook Yu, Kyungmi Oh, Jong-Won Chung, Oh. Young Bang, Gyeong-Moon Kim, Jin-Man Jung, Tae-Jin Song, Yong-Jae Kim, Bum Joon Kim, Sung Hyuk Heo, Kwang-Yeol Park, Jeong-Min Kim, Jong-Ho Park, Jay Chol Choi, Man-Seok Park, Joon- Tags: Full Length Article Source Type: research
Cost-effectiveness of dabigatran etexilate for the prevention of stroke and systemic embolism in atrial fibrillation in Taiwan
Abstract: Background: Economic evaluation of dabigatran, a new anti-antithrombotic agent, is done mostly in Western countries. It remains to be seen whether dabigatran will be cost effective in a practice environment where warfarin is significantly underused and the costs of both warfarin and international normalized ration INR monitoring are cheap.Methods: We performed a cost-effectiveness analysis with a Markov model to evaluate the value of dabigatran to prevent stroke and systemic embolism in patients with atrial fibrillation (AF) in Taiwan. Dabigatran was given through sequential dosing, where patients
Source: Thrombosis Research - March 17, 2014 Category: Hematology Authors: Chia-Hsien Chang, Yea-Huei Kao Yang, Jyh-Hong Chen, Li-Jen Lin Tags: Clinical Studies Source Type: research
Influence of the β-fibrinogen-455G/A polymorphism on development of ischemic stroke and coronary heart disease
Conclusion: Our meta-analysis suggests that the FGB-455G/A polymorphism contributes to susceptibility to IS and CHD.
Source: Thrombosis Research - January 21, 2014 Category: Hematology Authors: Lian Gu, Wenhui Liu, Yan Yan, Li Su, Guangliang Wu, Baoyun Liang, Jinjing Tan, Guihua Huang Tags: Clinical Studies Source Type: research
VASP phosphorylation and genetic polymorphism for clopidogrel resistance in Chinese patients with non-cardioembolic ischemic stroke
Clopidogrel resistance(CR)is found in non-cardioembolic ischemic stroke (NCIS) patients. However, it is still largely unknown how to identify CR in NCIS patients by laboratory and genetic characteristics.
Source: Thrombosis Research - October 10, 2014 Category: Hematology Authors: Shijun Zhang, Xinqiang Lai, Wenxian Li, Zhen Jing, Zhilin Xiong, Anding Xu, Yiwen Ruan, Li'an Huang Tags: Regular Article Source Type: research
Multidisciplinary Stepwise Management Strategy for Acute Superior Mesenteric Venous Thrombosis: An Intestinal Stroke Center Experience
BackgroudAcute superior mesenteric venous thrombosis (ASMVT) is an uncommon but catastrophic abdominal vascular emergency with high rate of intestinal failure and mortality. The retrospective pilot study was performed to assess the effect of a multidisciplinary stepwise management strategy on survival and mesenteric recanalization in an integrated intestinal stroke center (ISC).
Source: Thrombosis Research - November 10, 2014 Category: Hematology Authors: Shuofei Yang, Xinxin Fan, Weiwei Ding, Baochen Liu, Jiaxiang Meng, Dandan Xu, Changsheng He, Wenkui Yu, Xingjiang Wu, Jieshou Li Tags: Regular article Source Type: research
Anticoagulation for stroke prevention in new atrial fibrillation after coronary artery bypass graft surgery
The benefit of early anticoagulation for stroke prophylaxis in atrial fibrillation after coronary artery bypass graft (CABG) surgery is uncertain. We therefore studied what proportion of ischemic strokes in patients with atrial fibrillation early after CABG surgery were potentially preventable by anticoagulation with warfarin.
Source: Thrombosis Research - February 24, 2015 Category: Hematology Authors: S. Schulman, I. Cybulsky, J. Delaney Tags: Regular Article Source Type: research
Current use of oral contraceptives and the risk of first-ever ischemic stroke: A meta-analysis of observational studies
: To evaluate the risk of first-ever ischemic stroke associated with current use of oral contraceptive pills (OCPs), and to describe how the risk was influenced by estrogen dose, progestin type, and study characteristics.
Source: Thrombosis Research - April 24, 2015 Category: Hematology Authors: Zhenlin Xu, Ying Li, Shaowen Tang, Xiaoping Huang, Tong Chen Tags: Regular Article Source Type: research
Lack Of Tafi Increases Brain Damage And Microparticle Generation After Thrombolytic Therapy In Ischemic Stroke
Thrombin-activatable fibrinolysis inhibitor (TAFI) plays an important role in coagulation and fibrinolysis. Whereas TAFI deficiency may lead to a haemorrhagic tendency, data from TAFI knockout mice (TAFI−/−) are controversial and no differences have been reported in these animals after ischemic stroke. There are also no data regarding the role of circulating microparticles (MPs) in TAFI−/−.
Source: Thrombosis Research - June 10, 2015 Category: Hematology Authors: Orbe J, Alexandru N, Roncal C, Belzunce M, Bibiot P, Rodriguez JA, Meijers JCM, Georgescu A, Paramo JA Source Type: research
Warfarin non-persistence among stroke patients with atrial fibrillation
Warfarin treatment discontinuation is significant among patients with atrial fibrillation (AF). For AF patients with stroke a warfarin persistence rate of 0.45 after 2years has previously been reported. No consistent predictors for discontinuation have been established.
Source: Thrombosis Research - July 30, 2015 Category: Hematology Authors: Fredrik Björck, Henrik Renlund, Peter J. Svensson, Anders Själander Tags: Full length article Source Type: research
Warfarin persistence among stroke patients with atrial fibrillation
Warfarin treatment discontinuation is significant among patients with atrial fibrillation (AF). For AF patients with stroke a warfarin persistence rate of 0.45 after 2years has previously been reported. No consistent predictors for discontinuation have been established.
Source: Thrombosis Research - July 30, 2015 Category: Hematology Authors: Fredrik Björck, Henrik Renlund, Peter J. Svensson, Anders Själander Tags: Full Length Article Source Type: research
N2 extenuates experimental ischemic stroke through platelet aggregation inhibition
Thromboxane A2 (TXA2) can induce the platelet aggregation and lead to thrombosis. This will cause the low-reflow phenomenon after ischemic stroke and aggravate the damage of brain issues. Therefore, it is potential to develop the drugs inhibiting TXA2 pathway to treat cerebral ischemia.
Source: Thrombosis Research - October 29, 2015 Category: Hematology Authors: Lijian Yang, Xi Chen, Siqi Wang, Yuxiang Fei, Ding Wang, Yunman Li, Guangwei He, Qiang Wu, Shaoxing Chu, Weirong Fang Source Type: research
Association between rs1801133 polymorphism and risk of adult ischemic stroke: Meta-analysis based on case–control studies
This study is aimed to quantify the strength of the association between rs1801133 polymorphism and ischemic stroke risk.
Source: Thrombosis Research - December 1, 2015 Category: Hematology Authors: Min Chen, Ben Yu Mao, Dan Wang, Xianglin Cheng, Chuan Xin Xu Source Type: research
NETosis promotes cancer-associated arterial microthrombosis presenting as ischemic stroke with troponin elevation
Large elevations of high sensitive Troponin T (hsTnT) in ischemic stroke patients is associated with a poor outcome. In a pilot study we found a high prevalence of malignancies among these patients. Since neutrophil extracellular traps (NETs) have been linked to cancer-associated thrombosis, we hypothesized that the concomitant cerebral and myocardial ischemia could be the result of a NET-induced hypercoagulable state.
Source: Thrombosis Research - January 12, 2016 Category: Hematology Authors: Charlotte Thålin, Melanie Demers, Bo Blomgren, Siu Ling Wong, Magnus von Arbin, Anders von Heijne, Ann Charlotte Laska, Håkan Wallén, Denisa D. Wagner, Sara Aspberg Tags: Full Length Article Source Type: research
Cancer, other comorbidity, and risk of venous thromboembolism after stroke: a population-based cohort study
The impact of cancer and other comorbidity on the risk of venous thromboembolism (VTE) after stroke is poorly understood.
Source: Thrombosis Research - September 28, 2016 Category: Hematology Authors: Priscila Corraini, Anne Gulbech Ording, Victor W. Henderson, Szimonetta Sz épligeti, Erzsébet Horváth-Puhó, Henrik Toft Sørensen Tags: Original Article Source Type: research
