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Condition: Ischemic Stroke

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Total 66853 results found since Jan 2013.

Contribution of Established Stroke Risk Factors to the Burden of Stroke in Young Adults Clinical Sciences
Conclusions—Modifiable risk factors previously established in older populations also account for a large part of stroke in younger adults, with 4 risk factors explaining almost 80% of stroke risk.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00414583.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Annette Aigner, Ulrike Grittner, Arndt Rolfs, Bo Norrving, Bob Siegerink, Markus A. Busch Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Abnormal P-Wave Axis and Ischemic Stroke Clinical Sciences
Conclusions—aPWA is independently associated with ischemic stroke. This association seems to be stronger for cardioembolic strokes. Collectively, our findings suggest that alterations in atrial electric activation may predispose to cardiac thromboembolism independent of atrial fibrillation.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Ankit Maheshwari, Faye L. Norby, Elsayed Z. Soliman, Ryan J. Koene, Mary R. Rooney, Wesley T. O’Neal, Alvaro Alonso, Lin Y. Chen Tags: Arrhythmias, Electrophysiology, Ischemic Stroke Original Contributions Source Type: research

Workup for Perinatal Stroke Does Not Predict Recurrence Clinical Sciences
Conclusions—Thrombophilia, arteriopathy, or cardioembolic risk factors were not predictive of recurrent events after perinatal stroke. Thrombophilia evaluation in perinatal stroke should only rarely be considered.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Laura L. Lehman, Jeanette Beaute, Kush Kapur, Amy R. Danehy, Miya E. Bernson-Leung, Hayley Malkin, Michael J. Rivkin, Cameron C. Trenor III Tags: Pediatrics, Quality and Outcomes, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Mendelian Genes and Risk of Intracerebral Hemorrhage and Small-Vessel Ischemic Stroke in Sporadic Cases Brief Report
Conclusions—In the absence of syndromic features and family history of stroke, screening for Mendelian mutations among small-vessel stroke patients is unlikely to have high diagnostic utility.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Michael Chong, Martin O’Donnell, Vincent Thiȷs, Antonio Dans, Patricio Lopez–Jaramillo, Diego Gomez–Arbelaez, Charles Mondo, Anna Czlonkowska, Marta Skowronska, Shahram Oveisgharan, Salim Yusuf, Guillaume Pare Tags: Genetics, CADASIL, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Blood Biomarkers for the Early Diagnosis of Stroke Clinical Sciences
Conclusions—The studied biomarkers were not sufficient for an accurate differential diagnosis of stroke in the hyperacute setting. Additional discovery of new biomarkers and improvement on laboratory techniques seem necessary for achieving a molecular diagnosis of stroke.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Aleȷandro Bustamante, Elena Lopez–Cancio, Sara Pich, Anna Penalba, Dolors Giralt, Teresa Garcia–Berrocoso, Carles Ferrer–Costa, Teresa Gasull, Maria Hernandez–Perez, Monica Millan, Marta Rubiera, Pedro Cardona, Luis Cano, He Tags: Biomarkers, Clinical Studies, Diagnostic Testing, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Sodium Valproate, a Histone Deacetylase Inhibitor, Is Associated With Reduced Stroke Risk After Previous Ischemic Stroke or Transient Ischemic Attack Clinical Sciences
Conclusions—These results suggest that exposure to SVA, an inhibitor of HDAC, may be associated with a lower recurrent stroke risk although we cannot exclude residual confounding in this study design. This supports the hypothesis that HDAC9 is important in the ischemic stroke pathogenesis and that its inhibition, by SVA or a more specific HDAC9 inhibitor, is worthy of evaluation as a treatment to prevent recurrent ischemic stroke.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Rebecca L. Brookes, Siobhan Crichton, Charles D.A. Wolfe, Qilong Yi, Linxin Li, Graeme J. Hankey, Peter M. Rothwell, Hugh S. Markus Tags: Secondary Prevention, Genetics, Ischemic Stroke, Atherosclerosis Original Contributions Source Type: research

Stroke Incidence and Outcomes in Northeastern Greece Clinical Sciences
Conclusions—This is the largest to date population-based study in Greece documenting one of the highest stroke incidences ever reported in South Europe, highlighting the need for efficient stroke prevention and treatment strategies in Northeastern Greece.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Georgios Tsivgoulis, Athanasia Patousi, Maria Pikilidou, Theodosis Birbilis, Aristeidis H. Katsanos, Michalis Mantatzis, Aristeidis Asimis, Nikolaos Papanas, Panagiotis Skendros, Aikaterini Terzoudi, Aikaterini Karamanli, Ioannis Kouroumichakis, Pantelis Tags: Epidemiology, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Polygenic Risk for Depression Increases Risk of Ischemic Stroke Clinical Sciences
Conclusions—Higher polygenic risk for major depressive disorder is associated with increased risk of ischemic stroke overall and with small artery occlusion. Additional associations with ischemic stroke subtypes differed by ancestry.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Sylvia Wassertheil-Smoller, Qibin Qi, Tushar Dave, Braxton D. Mitchell, Rebecca D. Jackson, Simin Liu, Ki Park, Joel Salinas, Erin C. Dunn, Enrique C. Leira, Huichun Xu, Kathleen Ryan, Jordan W. Smoller Tags: Etiology, Mental Health, Genetic, Association Studies, Ischemic Stroke Original Contributions Source Type: research

Predictors of Thrombolysis Administration in Mild Stroke Clinical Sciences
Conclusions—Mild acutely presenting stroke patients are more likely to receive thrombolysis if they are young, white, or Hispanic and arrive early to the hospital with more severe neurological presentation. Identification of predictors of thrombolysis is important in design of future studies to assess the use of thrombolysis for mild stroke.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Negar Asdaghi, Kefeng Wang, Maria A. Ciliberti-Vargas, Carolina Marinovic Gutierrez, Sebastian Koch, Hannah Gardener, Chuanhui Dong, David Z. Rose, Enid J. Garcia, W. Scott Burgin, Juan Carlos Zevallos, Tatjana Rundek, Ralph L. Sacco, Jose G. Romano Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Role of Blood Lipids in the Development of Ischemic Stroke and its Subtypes Clinical Sciences
Conclusions—LDL cholesterol lowering is likely to prevent large artery atherosclerosis but may not prevent small artery occlusion nor cardioembolic strokes. High-density lipoprotein cholesterol elevation may lead to benefits in small artery disease prevention. Finally, triglyceride lowering may not yield benefits in ischemic stroke and its subtypes.
Source: Stroke - March 26, 2018 Category: Neurology Authors: George Hindy, Gunnar Engstrom, Susanna C. Larsson, Matthew Traylor, Hugh S. Markus, Olle Melander, Marȷu Orho–Melander Tags: Lipids and Cholesterol, Risk Factors, Ischemic Stroke Original Contributions Source Type: research

Frequency of Patent Foramen Ovale and Migraine in Patients With Cryptogenic Stroke Clinical Sciences
Conclusions—In patients with cryptogenic stroke who have migraine, there is a high prevalence (79%) of PFO with right-to-left shunt. The timing of the stroke in migraineurs is usually not related to a migraine attack. These observations are consistent with the hypothesis that the mechanism of stroke in migraineurs is most likely because of a paradoxical embolus. Future cryptogenic stroke classification schemes should consider including PFO as a separate etiologic category.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Brian H. West, Nabil Noureddin, Yakov Mamzhi, Christopher G. Low, Alexandra C. Coluzzi, Evan J. Shih, Rubine Gevorgyan Fleming, Jeffrey L. Saver, David S. Liebeskind, Andrew Charles, Jonathan M. Tobis Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Embolism Original Contributions Source Type: research

Acute Cerebrovascular Disease in the Young: The Stroke in Young Fabry Patients Study Original Contributions
Conclusions— Definite Fabry disease occurs in 0.5% and probable Fabry disease in further 0.4% of young stroke patients. Silent infarcts, white matter intensities, and classical risk factors were highly prevalent, emphasizing the need for new early preventive strategies. Clinical Trial Registration Information— URL: http://www.clinicaltrials.gov.Unique identifier: NCT00414583
Source: Stroke - January 18, 2013 Category: Neurology Authors: Rolfs, A., Fazekas, F., Grittner, U., Dichgans, M., Martus, P., Holzhausen, M., Bottcher, T., Heuschmann, P. U., Tatlisumak, T., Tanislav, C., Jungehulsing, G. J., Giese, A.-K., Putaala, J., Huber, R., Bodechtel, U., Lichy, C., Enzinger, C., Schmidt, R., Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Acute Stroke Syndromes, Genetics of Stroke Original Contributions Source Type: research

Socioeconomic Status and Care After Stroke: Results From the Registry of the Canadian Stroke Network Original Contributions
Conclusions— Higher income is associated with improvements in some aspects of stroke care delivery. However, the magnitude of the care gap across income quintiles is small and is unlikely to account for the previously observed association between socioeconomic status and survival after stroke.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Huang, K., Khan, N., Kwan, A., Fang, J., Yun, L., Kapral, M. K. Tags: Health policy and outcome research, Compliance/Adherence, Secondary prevention, Acute Stroke Syndromes, Other Stroke Treatment - Medical Original Contributions Source Type: research

The SOAR Stroke Score Predicts Inpatient and 7-Day Mortality in Acute Stroke Brief Reports
Conclusions— A simple score based on 4 easily obtainable variables at the point of care may potentially help predict early stroke mortality.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Kwok, C. S., Potter, J. F., Dalton, G., George, A., Metcalf, A. K., Ngeh, J., Nicolson, A., Owusu-Agyei, P., Shekhar, R., Walsh, K., Warburton, E. A., Myint, P. K., On behalf of the Anglia Stroke Clinical Network Evaluation Study (ASCNES) Group Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction Brief Reports Source Type: research

Quality of Acute Ischemic Stroke Care in Thailand: A Prospective Multicenter Countrywide Cohort Study
Conclusions: Limited access to acute ischemic stroke care interventions were observed in many domains especially thrombolysis and stroke unit admission. These findings emphasize an urgent need for strategies to improve standard acute stroke care among developing countries.
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2013 Category: Neurology Authors: Yongchai Nilanont, Samart Nidhinandana, Nijasri C. Suwanwela, Suchat Hanchaiphiboolkul, Taksin Pimpak, Pyatat Tatsanavivat, Gustavo Saposnik, Niphon Poungvarin, Thai Stroke Registry Tags: Original Articles Source Type: research