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Source: UCLA Newsroom: Health Sciences
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Total 132 results found since Jan 2013.
Today's statin users consume more calories and fat, and weigh more, than their predecessors
People who take statin drugs to lower their cholesterol appear to have developed a false sense of security that could lead to heart disease and other obesity-related illnesses.
A new UCLA-led study suggests that people who took statins in the 2009–10 year were consuming more calories and fat than those who used statins 10 years earlier. There was no similar increase in caloric and fat intake among non–stain users during that decade, researchers said.
In 1999–2000, statin users were consuming fewer calories and less fat than individuals who didn't take these medications, but that is no longer the case. Increase...
Source: UCLA Newsroom: Health Sciences - April 25, 2014 Category: Universities & Medical Training Source Type: news
Stroke treatment, outcomes improve at hospitals participating in UCLA-led initiative
Administering a clot-dissolving drug to stroke victims quickly — ideally within the first 60 minutes after they arrive at a hospital emergency room — is crucial to saving their lives, preserving their brain function and reducing disability.
Given intravenously, tPA (tissue plasminogen activator) is currently the only Food and Drug Administration–approved therapy shown to improve outcomes for patients suffering acute ischemic stroke, which affects some 800,000 Americans annually.
Now, a UCLA-led study demonstrates that hospitals participating in the "Target: Stroke" national quality-improvement program have markedly...
Source: UCLA Newsroom: Health Sciences - April 23, 2014 Category: Universities & Medical Training Source Type: news
Potassium in brain could be key to fighting Huntington's disease
By boosting the ability of a specific type of cell to absorb potassium in the brain, UCLA researchers were able to improve walking and prolong survival in a mouse model of Huntington's disease.
Their findings, published March 30 in the online edition of the journal Nature Neuroscience, could point to new drug targets for treating the devastating disease, which strikes one in every 20,000 Americans.
Huntington's disease is passed from parent to child through a mutation in the huntingtin gene. By killing brain cells called neurons, the disorder gradually deprives patients of their ability to walk, speak, swallow, breat...
Source: UCLA Newsroom: Health Sciences - March 31, 2014 Category: Universities & Medical Training Source Type: news
Tweaking potassium levels in brain could be a key to fighting Huntington's disease
By boosting the ability of a specific type of cell to absorb potassium in the brain, UCLA researchers were able to improve walking and prolong survival in a mouse model of Huntington's disease.
Their findings, published March 30 in the online edition of the journal Nature Neuroscience, could point to new drug targets for treating the devastating disease, which strikes one in every 20,000 Americans.
Huntington's disease is passed from parent to child through a mutation in the huntingtin gene. By killing brain cells called neurons, the disorder gradually deprives patients of their ability to walk, speak, sw...
Source: UCLA Newsroom: Health Sciences - March 31, 2014 Category: Universities & Medical Training Source Type: news
Quick magnesium treatment fails to improve stroke outcomes, but study has silver lining
In the first study of its kind, a consortium led by UCLA physicians found that giving stroke patients intravenous magnesium within an hour of the onset of symptoms does not improve stroke outcomes.
However, the 8-year trial did find that with the help of paramedics in the field, intravenous medications can frequently be administered to stroke victims within that so-called "golden hour," during which they have the best chance to survive and avoid debilitating, long-term neurological damage.
The latter finding is a "game-changer," said Dr. Jeffrey Saver, director of the UCLA Stroke Center and a professor of ...
Source: UCLA Newsroom: Health Sciences - February 13, 2014 Category: Universities & Medical Training Source Type: news
Researchers ID more pesticides linked to Parkinson's, gene that increases risk
This report provides evidence for the relevance of ALDH inhibition in Parkinson's disease pathogenesis, identifies pesticides that should be avoided to reduce the risk of developing Parkinson's disease and suggests that therapies modulating ALDH enzyme activity or otherwise eliminating toxic aldehydes should be developed and tested to potentially reduce Parkinson's disease occurrence or slow its progression, particularly for patients exposed to pesticides," the study states.
The study was funded in part by the National Institute of Environmental Health Sciences (P01ES016732, R01ES010544, 5R21ES16446-2 and U54ES0120...
Source: UCLA Newsroom: Health Sciences - February 3, 2014 Category: Universities & Medical Training Source Type: news
Tomato therapy: Engineered veggies target intestinal lipids, improve cholesterol
UCLA researchers report that tiny amounts of a specific type of lipid in the small intestine may play a greater role than previously thought in generating the high cholesterol levels and inflammation that lead to clogged arteries.
The team also found they could reduce the negative effects of these lipids in mice by feeding the animals a new genetically engineered tomato being developed at UCLA that is designed to mimic HDL ("good") cholesterol.
The study, published in the December issue of the Journal of Lipid Research with an accompanying editorial, focused on a group of lipids found in the sma...
Source: UCLA Newsroom: Health Sciences - November 13, 2013 Category: Universities & Medical Training Source Type: news
Hospitals in GWTG-Stroke program more likely to provide recommended stroke treatment
Timely stroke treatment is critical to ensuring good outcomes for patients. A new national study compared two programs designed to help hospitals adhere to nationally accepted standards and guideline recommendations for stroke treatment and found that hospitals participating in the Get With The Guidelines–Stroke program were more likely than Primary Stroke Center–certified hospitals to provide all the guideline-based measures of care for patients.
The study appears in the Oct. 14 issue of the Journal of the American Heart Association.
The American Heart Association/American Stroke Association's ...
Source: UCLA Newsroom: Health Sciences - October 15, 2013 Category: Universities & Medical Training Source Type: news
UCLA, USC get $2M to develop stroke center network in Southland
Stroke is the second leading cause of death in Los Angeles County and the fourth in the U.S. In order to cut those numbers, it's imperative that new treatments be developed and refined for stroke prevention, acute therapy and recovery after stroke.
Now, a three-way partnership between the UCLA Stroke Center at Ronald Reagan UCLA Medical Center, the USC Comprehensive Stroke and Cerebrovascular Center at Keck Medicine of USC, and UC Irvine has been awarded a $2 million grant from the National Institutes of Health to address these three stroke priorities.
Together, the three universities will form the Los A...
Source: UCLA Newsroom: Health Sciences - October 15, 2013 Category: Universities & Medical Training Source Type: news
Lack of parental warmth, abuse in childhood linked to multiple health risks in adulthood
This study was also supported by the MacArthur Research Network on Socioeconomic Status and Health through grants from the John D. and Catherine T. MacArthur Foundation, and by grant T32-MH19925 and the Cousins Center for Psychoneuroimmunology at the UCLA.
The UCLA Cousins Center for Psychoneuroimmunology encompasses an interdisciplinary network of scientists working to advance the understanding of psychoneuroimmunology by linking basic and clinical research programs and by translating findings into clinical practice. The center is affiliated with the Semel Institute for Neuroscience and Human Behavior and the David...
Source: UCLA Newsroom: Health Sciences - October 1, 2013 Category: Universities & Medical Training Source Type: news
California Health Interview Survey releases new 2011-12 data on health of Californians
The California Health Interview Survey (CHIS) today released new data based on interviews with more than 44,000 households in California. The survey, conducted by the UCLA Center for Health Policy Research, covered hundreds of topics affecting state residents' health and well-being. (See a complete list of topics here.)
Data on nearly 200 of these topics were released today on AskCHIS, the center's award-winning, free, easy-to-use Web tool that provides data by state, region, county and some service-planning areas in Los Angeles and San Diego counties. Even more data were released through free, downloadable pub...
Source: UCLA Newsroom: Health Sciences - August 8, 2013 Category: Universities & Medical Training Source Type: news
Growth, not just size, boosts brain aneurysms' risk of bursting
Brain aneurysms of all sizes — even small ones the size of a pea — are up to 12 times more likely to rupture if they are growing, according to a new UCLA study.
Published July 2 in the online edition of the journal Radiology, the discovery counters current guidelines suggesting that small aneurysms pose a low risk for rupture, and it emphasizes the need for regular monitoring and earlier treatment.
"Until now, we believed that large aneurysms presented the highest risk for rupture and that smaller aneurysms may not require monitoring," said lead author Dr. J. Pablo Villablanca, chief of diagn...
Source: UCLA Newsroom: Health Sciences - July 2, 2013 Category: Universities & Medical Training Source Type: news
Timely treatment after stroke is crucial, UCLA researchers report
For years, the mantra of neurologists treating stroke victims has been "time equals brain." That's because getting a patient to the emergency room quickly to receive a drug that dissolves the stroke-causing blood clot can make a significant difference in how much brain tissue is saved or lost.
But specific information has been limited on just how the timing of giving the intravenous drug — known as a tissue plasminogen activator, or tPA — influences outcomes for victims of ischemic (clot-caused), stroke, the most common type of stroke.
Now, a team led by UCLA researchers has conducted a major stud...
Source: UCLA Newsroom: Health Sciences - June 18, 2013 Category: Universities & Medical Training Source Type: news
Fat chance: Scientists unexpectedly discover stress-resistant stem cells in adipose tissue
Researchers from the UCLA Department of Obstetrics and Gynecology have isolated a new population of primitive, stress-resistant human pluripotent stem cells that are easily derived from fat tissue and are able to differentiate into virtually every cell type in the human body without genetic modification.
The cells, called multi-lineage stress-enduring stem cells from adipose tissue (Muse-AT), were discovered by "scientific accident" when a piece of equipment failed in the laboratory, killing all the stem cells in an experiment except the Muse-AT cells.
The UCLA team further discovered that not only are Muse-A...
Source: UCLA Newsroom: Health Sciences - June 5, 2013 Category: Universities & Medical Training Source Type: news
Brain rewires itself after damage or injury, life scientists discover
When the brain's primary "learning center" is damaged, complex new neural circuits arise to compensate for the lost function, say life scientists from UCLA and Australia who have pinpointed the regions of the brain involved in creating those alternate pathways — often far from the damaged site.
The research, conducted by UCLA's Michael Fanselow and Moriel Zelikowsky in collaboration with Bryce Vissel, a group leader of the neuroscience research program at Sydney's Garvan Institute of Medical Research, appears this week in the early online edition of the journal Proceedings of the National Academy of Sciences.
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Source: UCLA Newsroom: Health Sciences - May 15, 2013 Category: Universities & Medical Training Source Type: news
