• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

The Development of Neuroimaging Biomarkers for Cognitive Decline in Sickle Cell Disease
Sickle cell disease (SCD) is complicated by neurologic complications including vasculopathy, hemorrhagic or ischemic overt stroke, silent cerebral infarcts and cognitive dysfunction. Patients with SCD, even in the absence of vasculopathy or stroke, have experience cognitive dysfunction that progresses with age. Transcranial Doppler ultrasound and structural brain MRI are currently used for primary and secondary stroke prevention, but laboratory or imaging biomarkers do not currently exist that are specific to the risk of cognitive dysfunction in patients with SCD. Recent investigations have used advanced MR sequences asses...
Source: Hematology/Oncology Clinics of North America - November 16, 2022 Category: Cancer & Oncology Authors: Kristie Ramos, Kristin P. Guilliams, Melanie E. Fields Source Type: research

Neuroimaging in Central Nervous System Lymphoma
Primary central nervous system lymphoma (PCNSL) is a rare aggressive high-grade type of extranodal lymphoma. PCNSL can have a variable imaging appearance and can mimic other brain disorders such as encephalitis, demyelination, and stroke. In addition to PCNSL, the CNS can be secondarily involved by systemic lymphoma. Computed tomography and conventional MRI are the initial imaging modalities to evaluate these lesions. Recently, however, advanced MRI techniques are more often used in an effort to narrow the differential diagnosis and potentially inform diagnostic and therapeutic decisions.
Source: Hematology/Oncology Clinics of North America - July 28, 2016 Category: Cancer & Oncology Authors: Seyed Ali Nabavizadeh, Arastoo Vossough, Mehrdad Hajmomenian, Reza Assadsangabi, Suyash Mohan Source Type: research

Imaging Manifestations of Neurologic Complications in Anemia
The hallmark signs and symptoms of anemia are directly related to a decrease in oxygen delivery to vital tissues and organs and include pallor, fatigue, lightheadedness, and shortness of breath. Neurologic complications are often nonspecific and can include poor concentration, irritability, faintness, tinnitus, and headache. If undiagnosed or untreated, anemia can progress to cognitive dysfunction, psychosis, encephalopathy, myelopathy, peripheral neuropathy, and more focal syndromes, such as stroke, seizures, chorea, and transverse myelitis. Imaging can play an important role in the early diagnosis and treatment of these ...
Source: Hematology/Oncology Clinics of North America - June 6, 2016 Category: Cancer & Oncology Authors: Ritesh Patel, Shyam Sabat, Sangam Kanekar Source Type: research

Management of Patients with Sickle Cell Disease Using Transfusion Therapy
Red blood cell (RBC) transfusion therapy is a key component of comprehensive management of patients with sickle cell disease (SCD) and has increased over time as a means of primary and secondary stroke prevention. RBC transfusions also prove to be lifesaving for many acute sickle cell–related complications. Although episodic and chronic transfusion therapy has significantly improved the morbidity and mortality of patients with SCD, transfusions are not without adverse effects. This review addresses RBC transfusion methods, evidence-based and/or expert panel–based consensus on indications for chronic and episodic transf...
Source: Hematology/Oncology Clinics of North America - April 23, 2016 Category: Cancer & Oncology Authors: Stella T. Chou, Ross M. Fasano Source Type: research