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Effects of tumor type on outcomes in patients with large vessel occlusion stroke and cancer
Large vessel occlusions (LVO) stroke is associated with cancer. Whether this association differs among patients with LVO that undergo endovascular thrombectomy (EVT) according to cancer type remains unknown.
Source: Journal of Stroke and Cerebrovascular Diseases - August 3, 2023 Category: Neurology Authors: F. Shalabi, S. Aladdin, J. Molad, Z. Itsekzon-Hayosh, T. Sacagiu, A. Honig, H. Halevi, D. Orion, J.M. Gomori, J.E. Cohen, Ronen R. Leker Source Type: research

Quality-of-life, concerns, and treatment priorities in patients with cancer-related ischemic stroke: A prospective survey study
Comorbid cancer with stroke is a complex situation with multiple factors affecting quality of life (QoL). No specific questionnaire exists to assess current drivers of QoL and future concerns and priorities in patients with cancer-related stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 2, 2023 Category: Neurology Authors: Judy Dawod, Mohammad Hossein Abbasi, Babak B. Navi, Scott E. Kasner Source Type: research

Risk of intracranial hemorrhage with direct oral anticoagulation versus low molecular weight heparin in the treatment of brain tumor-associated venous thromboembolism: A meta-analysis
Direct oral anticoagulants (DOACs) are effective in treating cancer-related thrombosis and are superior to low molecular weight heparin (LMWH) in terms of efficacy. The effects of DOACs or LMWH on intracranial hemorrhage (ICH) remain uncertain in individuals with brain tumors. We conducted a meta-analysis to compare the frequency of ICH in individuals with brain tumors treated with DOACs or LMWH.
Source: Journal of Stroke and Cerebrovascular Diseases - July 4, 2023 Category: Neurology Authors: Jun Yang, Zesong He, Meihua Li, Tao Hong, Taohui Ouyang Source Type: research

Stroke as a cause of death in patients with cancer: a SEER-based study
Death from stroke is linked to cancer due to its pathogenesis and side effects of treatment. Despite this, guidelines regarding identifying cancer patients at the highest risk of mortality from stroke are unclear.
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2023 Category: Neurology Authors: Yousef Tarek Sonbol, Anas Elgenidy, Ahmed K. Awad, Ahmed O. Elmehrath, Hassan Kobeissi, Ahmed M. Afifi, Sherief Ghozy Source Type: research

Trends in age and sex-specific prevalence of cancer and cancer subtypes in acute ischemic stroke from 2007-2019
To describe age and sex-specific prevalence of cancer in acute ischemic stroke (AIS) hospitalizations in the United States over the last decade.
Source: Journal of Stroke and Cerebrovascular Diseases - October 29, 2022 Category: Neurology Authors: Fadar Oliver Otite, Sana Somani, Ehimen Aneni, Emmanuel Akano, Smit D. Patel, Nnabuchi Anikpezie, Olaoluwatomi Lamikanra, Hesham Masoud, Julius Gene Latorre, Seemant Chaturvedi, Prachi Mehndiratta Source Type: research

Clinical features and prognostic factors in patients with cancer-associated multiple ischemic stroke: A retrospective observational study
Cancer causes coagulation abnormalities in arterial and venous systems.1,2 A highly active cancer is an established risk factor of ischemic stroke,3 and patients with cancer sometimes receive additional burden due to cancer-associated ischemic stroke (CAIS).4,5 Multiple cerebral infarctions involving various cerebrovascular territories in cryptogenic CAIS, referred to as “multiple CAIS” in this report, are of particular clinical interest since they lead to poor prognosis, with a median survival of at most a few months.
Source: Journal of Stroke and Cerebrovascular Diseases - October 21, 2022 Category: Neurology Authors: Jun Tanimura, Tomokiyo Yamamoto, Takao Hashimoto Source Type: research

Mutation of breast cancer susceptibility genes increases cerebral microbleeds: A pilot study
Growing evidence suggests breast cancer susceptibility gene (BRCA) mutations may augment cerebrovascular risk factors. With this influence in mind, we aimed to identify if BRCA mutations increased the prevalence of cerebral small vessel disease (CSVD).
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2022 Category: Neurology Authors: Brandon Pope, Zoe Wolcott, Marissa Castillo, Jacqueline Jin, Ka-Ho Wong, Adam de Havenon, Shadi Yaghi, Eric D. Goldstein Source Type: research

Endovascular Treatment for Acute Ischemic Stroke After Video-Assisted Thoracoscopic Pulmonary Lobectomy in Patients With Lung Cancer: A Report of Four Cases and Literature Review
Postoperative cerebral embolic stroke is a serious complication of pulmonary lobectomy, occurring in 1.1% of patients undergoing lobectomy through video-assisted thoracoscopic surgery (VATS). The mechanism of this complication is thought to be embolic stroke caused by thrombus formed due to stagnation in the pulmonary vein stump after VATS lobectomy. There have been few reports demonstrating the utility of endovascular treatment (EVT) for cerebral embolic stroke after VATS lobectomy.
Source: Journal of Stroke and Cerebrovascular Diseases - June 10, 2022 Category: Neurology Authors: Hiroshi Ueno, Hiroto Yamaoka, Sakyo Hirai, Kyohei Fujita, Mariko Ishikawa, Shoko Fujii, Yuki Aizawa, Yosuke Ishii, Masataka Yoshimura, Kenji Yamada, Yoshikazu Yoshino, Morito Kurata, Katsutoshi Seto, Hironori Ishibashi, Kenichi Okubo, Shigeru Nemoto, Kazu Tags: Case Report Source Type: research

Endovascular Therapy is Effective for Large Vessel Occlusion Despite Concurrent Cancer
Ischemic stroke and concurrent cancer is increasingly recognized. However, optimal management is uncertain. As mechanical thrombectomy has become the standard of care for large vessel occlusion, more patients with cancer are presenting for embolectomy. However, it is unknown whether this subgroup has the same benefit profile described in multiple randomized trials for thrombectomy for large vessel occlusion. Our objective was to retrospectively evaluate a North American embolectomy database for safety and outcomes in patients with active cancer.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2022 Category: Neurology Authors: Thomas K. Mattingly, Jorge E. Risco, Jaclyn E. Burch, Raquel Whyte, Gurkirat S. Kohli, Stephen Susa, Tarun Bhalla, Matthew T. Bender Source Type: research

Adherence to Guideline-Recommended Cancer Screening in Stroke Survivors: A Nationwide Analysis
Cancer can present as stroke. Several cancer types have established screening guidelines. We investigated adherence to guideline-recommended cancer screening in stroke survivors versus the general population.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2022 Category: Neurology Authors: Marialaura Simonetto, Stephanie Rutrick, Natalie M. LeMoss, Kelsey N. Lansdale, Scott T. Tagawa, Hooman Kamel, Neal Parikh, Babak B. Navi Source Type: research

Understanding Coordinator Roles in Acute Stroke Care: A National Survey
Globally, stroke is a major contributor to death and disability.1 Evidence-based care in hospital after an acute stroke ensures improved survival and reduced disability, but care quality can vary.2,3 Clinical coordinators have an essential role in improving best-practice in trauma, cancer, diabetes, and heart failure conditions.4-7 Within stroke, coordinator roles are not new; in 1970, a study outlining the ‘Stroke Team’ model was published, which included a physician, nurse-coordinator and physical therapist.
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2021 Category: Neurology Authors: Tara Purvis, Sandy Middleton, Anne W. Alexandrov, Monique F. Kilkenny, Skye Coote, Sarah Kuhle, Dominique A. Cadilhac Source Type: research

Elevated CA125 is Related to Stroke Due to Cancer- Associated Hypercoagulation
It is well-known that cancer patients commonly have ischemic stroke and the incidence is getting increased with the development of cancer therapy prolonging survival.1 Ischemic stroke in cancer patients is caused by various etiologies. Cancer-associated hypercoagulation is one of the major important pathophysiological mechanisms of stroke in cancer patients.2,3 This hypercoagulation is mediated by multiple mechanisms associated with tissue factor, mucin, and cysteine proteinase. Carcinomatous mucins are considered to trigger thrombogenicity by interacting with P and L selectins and inducing the formation of platelet-rich microthrombi.
Source: Journal of Stroke and Cerebrovascular Diseases - September 27, 2021 Category: Neurology Authors: Keiko Maezono-Kandori, Tomoyuki Ohara, Jun Fujinami, Naoki Makita, Eijirou Tanaka, Toshiki Mizuno Source Type: research

Association Between Weight Loss and Activities of Daily Living in Obese and Overweight Patients after Stroke: A Cross-Sectional Study
Obesity is an important issue in global health care. Between 1975 and 2016, the proportion of obese individuals in the world nearly tripled. In fact, 39% of adults aged 18 years and older were overweight in 2016 and 13% were obese, using the traditional definition of overweight and obesity, namely, a body mass index (BMI)> 25 kg/m2 and> 30 kg/m2, respectively.1 Obesity is associated with a significant increase in mortality2,3 and the risk of many disorders, including metabolic and cardiovascular disease,4 cancer,5 infection,6 and physical limitations,7 as well as increasing healthcare costs.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2021 Category: Neurology Authors: Yoji Kokura, Shinta Nishioka Source Type: research

Endovascular Treatment of Carotid Blowout Syndrome
Carotid blowout syndrome (CBS) is a life-threatening disease characterized by compromise of the carotid artery by head and neck cancer (HNC).
Source: Journal of Stroke and Cerebrovascular Diseases - May 25, 2021 Category: Neurology Authors: Yuu Simizu Source Type: research

Reperfusion Therapy in Acute Ischemic Stroke with Active Cancer: A Meta-Analysis Aided by Machine Learning
While the prevalence of active cancer patients experiencing acute stroke is increasing, the effects of active cancer on reperfusion therapy outcomes are inconclusive. Thus, we aimed to compare the safety and outcomes of reperfusion therapy in acute stroke patients with and without active cancer.
Source: Journal of Stroke and Cerebrovascular Diseases - March 26, 2021 Category: Neurology Authors: Mi-Yeon Eun, Eun-Tae Jeon, Kwon-Duk Seo, Dongwhane Lee, Jin-Man Jung Source Type: research

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